Last decade's advances and modern aspects of near infrared spectroscopy are critically
examined and reviewed. Innovative instrumentation, highlighted by portable and imaging …

Various frameworks and methods, such as quality by design (QbD), real time release test
(RTRT), and continuous process verification (CPV), have been introduced to improve drug …

Quality is the lifeline for all pharmaceuticals. Process analytical technology (PAT),
introduced by FDA in 2004, providing significant opportunities for improving pharmaceutical …

The fluidized bed granulation and pellets coating technologies are widely used in
pharmaceutical industry, because the particles made in a fluidized bed have good …

Background Continuous manufacturing, a new process that applies the concept of time
rather than batch size, is gradually being implemented throughout the pharmaceutical …

A combination of computational fluid dynamics (CFD), discrete element method (DEM), and
discrete droplet method (DDM), ie, a CFD-DEM-DDM model, was developed to simulate …

Fluidized beds are used by pharmaceutical manufacturers for multi-particulate drug coating.
They provide effective mass and heat transfer; however, unit optimization can be difficult due …

Particle size distribution (PSD) is often considered as critical material attribute for active
pharmaceutical ingredients (APIs), and the need for regular evaluation stands as an …

Although near infrared (NIR) spectra are primarily influenced by undesired variations, ie,
baseline shifts and non-linearity, and many applications of NIR spectroscopy to the real-time …

Abstract Quality by Design (QbD) for the pharmaceutical industry includes the design,
development and production control of products and production processes from the …