Cut the noise or couple up: Coordinating circadian and synthetic clocks
CN Micklem, JCW Locke - Iscience, 2021 - cell.com
Circadian clocks are important to much of life on Earth and are of inherent interest to
humanity, implicated in fields ranging from agriculture and ecology to developmental biology …
humanity, implicated in fields ranging from agriculture and ecology to developmental biology …
[HTML][HTML] Heterogeneity of neuronal properties determines the collective behavior of the neurons in the suprachiasmatic nucleus
Circadian rhythms have been observed in behavioral and physiological activities of living
things exposed to the natural 24 h light-darkness cycle. Interestingly, even under constant …
things exposed to the natural 24 h light-darkness cycle. Interestingly, even under constant …
Noise-driven cellular heterogeneity in circadian periodicity
Nongenetic cellular heterogeneity is associated with aging and disease. However, the
origins of cell-to-cell variability are complex and the individual contributions of different …
origins of cell-to-cell variability are complex and the individual contributions of different …
Measuring relative coupling strength in circadian systems
Modern imaging techniques allow the monitoring of circadian rhythms of single cells.
Coupling between these single cellular circadian oscillators can generate coherent periodic …
Coupling between these single cellular circadian oscillators can generate coherent periodic …
[HTML][HTML] Diurnal variations of resting-state fMRI data: A graph-based analysis
Circadian rhythms (lasting approximately 24 h) control and entrain various physiological
processes, ranging from neural activity and hormone secretion to sleep cycles and eating …
processes, ranging from neural activity and hormone secretion to sleep cycles and eating …
Synchronization in slowly switching networks of coupled oscillators
Networks whose structure of connections evolves in time constitute a big challenge in the
study of synchronization, in particular when the time scales for the evolution of the graph …
study of synchronization, in particular when the time scales for the evolution of the graph …
Heritable gene expression variability and stochasticity govern clonal heterogeneity in circadian period
A ubiquitous feature of the circadian clock across life forms is its organization as a network of
cellular oscillators, with individual cellular oscillators within the network often exhibiting …
cellular oscillators, with individual cellular oscillators within the network often exhibiting …
Diversity-induced trivialization and resilience of neural dynamics
Heterogeneity is omnipresent across all living systems. Diversity enriches the dynamical
repertoire of these systems but remains challenging to reconcile with their manifest …
repertoire of these systems but remains challenging to reconcile with their manifest …
Heterogeneity in GnRH and kisspeptin neurons and their significance in vertebrate reproductive biology
Vertebrate reproduction is essentially controlled by the hypothalamus-pituitary–gonadal
(HPG) axis, which is a central dogma of reproductive biology. Two major hypothalamic …
(HPG) axis, which is a central dogma of reproductive biology. Two major hypothalamic …
The synchronization of neuronal oscillators determined by the directed network structure of the suprachiasmatic nucleus under different photoperiods
The main function of the principal clock located in the suprachiasmatic nucleus (SCN) of
mammals is synchronizing the body rhythms to the 24 h light-dark cycle. Additionally, the …
mammals is synchronizing the body rhythms to the 24 h light-dark cycle. Additionally, the …