The role of microRNAs in neurodegenerative diseases: a review
S Li, Z Lei, T Sun - Cell Biology and Toxicology, 2023 - Springer
MicroRNAs (miRNAs) are non-coding RNAs which are essential post-transcriptional gene
regulators in various neuronal degenerative diseases and playact a key role in these …
regulators in various neuronal degenerative diseases and playact a key role in these …
The epigenetics of aging and neurodegeneration
Epigenetics is a quickly growing field encompassing mechanisms regulating gene
expression that do not involve changes in the genotype. Epigenetics is of increasing …
expression that do not involve changes in the genotype. Epigenetics is of increasing …
Gene expression elucidates functional impact of polygenic risk for schizophrenia
Over 100 genetic loci harbor schizophrenia-associated variants, yet how these variants
confer liability is uncertain. The CommonMind Consortium sequenced RNA from …
confer liability is uncertain. The CommonMind Consortium sequenced RNA from …
Temporal dynamics and genetic control of transcription in the human prefrontal cortex
Previous investigations have combined transcriptional and genetic analyses in human cell
lines,,, but few have applied these techniques to human neural tissue,,,,. To gain a global …
lines,,, but few have applied these techniques to human neural tissue,,,,. To gain a global …
Phenotypic differences in hiPSC NPCs derived from patients with schizophrenia
Consistent with recent reports indicating that neurons differentiated in vitro from human-
induced pluripotent stem cells (hiPSCs) are immature relative to those in the human brain …
induced pluripotent stem cells (hiPSCs) are immature relative to those in the human brain …
[HTML][HTML] Human stem cell models of neurodegeneration: From basic science of amyotrophic lateral sclerosis to clinical translation
Neurodegenerative diseases are characterized by progressive cell loss leading to disruption
of the structure and function of the central nervous system. Amyotrophic lateral sclerosis …
of the structure and function of the central nervous system. Amyotrophic lateral sclerosis …
Emerging roles of non-coding RNAs in brain evolution, development, plasticity and disease
IA Qureshi, MF Mehler - Nature Reviews Neuroscience, 2012 - nature.com
Novel classes of small and long non-coding RNAs (ncRNAs) are being characterized at a
rapid pace, driven by recent paradigm shifts in our understanding of genomic architecture …
rapid pace, driven by recent paradigm shifts in our understanding of genomic architecture …
Neuron secrete exosomes containing miR-9-5p to promote polarization of M1 microglia in depression
X Xian, LL Cai, Y Li, RC Wang, YH Xu, YJ Chen… - Journal of …, 2022 - Springer
Background Neuroinflammation is an important component mechanism in the development
of depression. Exosomal transfer of MDD-associated microRNAs (miRNAs) from neurons to …
of depression. Exosomal transfer of MDD-associated microRNAs (miRNAs) from neurons to …
Modeling key pathological features of frontotemporal dementia with C9ORF72 repeat expansion in iPSC-derived human neurons
S Almeida, E Gascon, H Tran, HJ Chou… - Acta …, 2013 - Springer
The recently identified GGGGCC repeat expansion in the noncoding region of C9ORF72 is
the most common pathogenic mutation in patients with frontotemporal dementia (FTD) or …
the most common pathogenic mutation in patients with frontotemporal dementia (FTD) or …
miR-9: a versatile regulator of neurogenesis
M Coolen, S Katz, L Bally-Cuif - Frontiers in cellular neuroscience, 2013 - frontiersin.org
Soon after its discovery, microRNA-9 (miR-9) attracted the attention of neurobiologists, since
it is one of the most highly expressed microRNAs in the developing and adult vertebrate …
it is one of the most highly expressed microRNAs in the developing and adult vertebrate …