Advances in genotyping technology have, over the past decade, enabled the focused
search for common genetic variation associated with human diseases and traits. With the …

With the availability of DNA-based molecular markers during early 1980s and that of
sophisticated statistical tools in late 1980s and later, it became possible to identify genomic …

To make predictions and explore large datasets, healthcare is increasingly applying
advanced algorithms of artificial intelligence. However, to make well‐considered and …

We tackle the problem of selecting from among a large number of variables those that are
“important” for an outcome. We consider situations where groups of variables are also of …

Phenome-wide association study (PheWAS) has been increasingly used to identify novel
genetic associations across a wide spectrum of phenotypes. This systematic review aims to …

Embracing the complexity of biological systems has a greater likelihood to improve
prediction of clinical drug response. Here we discuss limitations of a singular focus on …

The Handbook of Reliability, Maintenance, and System Safety through Mathematical
Modeling discusses the many factors affect reliability and performance, including …

Advances in quantitative genetics have enabled researchers to identify genomic regions
associated with changes in phenotype. However, genomic regions can contain hundreds to …

The last couple decades have seen the proliferation of high-throughput biological assays as
well as the use of electronic medical records for research purposes. For example, the UK …