Quality-of-life improvements have resulted in increasing attention being paid to research on
antiaging and antioxidation. Polyphenols are natural antioxidants with excellent biological …

Cis-diamminedichloridoplatinum (II)(cisplatin) is a chemotherapeutic drug currently
prescribed for the treatment of many types of human cancer, but its use is associated with …

Spiral ganglion neurons (SGNs) are auditory neurons that relay sound signals from the inner
ear to the brainstem. The ototoxic drug cisplatin can damage SGNs and thus lead to …

Paraquat (PRQ) is a toxic chemical compound that is very noxious to animals and humans.
Gallic acid is a phenolic compound that has antioxidant properties. In this study, we …

Cisplatin is an important antineoplastic drug used in multiple chemotherapeutic regimens
but unfortunately causes serious toxic effects as ovarian and uterine toxicity. This study …

Background/Aim Diclofenac (DIC) is a Nonsteroidal anti-inflammatory drug (NSAID) and
consumption of this drug creates side effects such as renal injury. The purpose of this work …

Background Side effects of cisplatin (CIS) such as testicular toxicity restrict its clinical use.
Instead, evidence indicates that crocin (CR) has synergistic anti-cancer potential with CIS …

The aim of the present study was to evaluate the protective effect of gallic acid (GA) against
cisplatin (CDDP)-induced ovarian toxicity, for the first time. The ovarian damage was …

Testicular dysfunction or damage is among the critical side effects of chemotherapeutic
drugs like cisplatin. This study was mapped out to assess the possible therapeutic effect of …

Objective. This study aimed to investigate the effects of gallic acid and silymarin against
nephrotoxicity and hepatotoxicity caused by cisplatin. Materials and Methods. In the study …