Role of human milk bioactives on infants' gut and immune health

LE Carr, MD Virmani, F Rosa, D Munblit… - Frontiers in …, 2021 - frontiersin.org
Exclusive human milk feeding of the newborn is recommended during the first 6 months of
life to promote optimal health outcomes during early life and beyond. Human milk contains a …

Probiotics, prebiotics and epithelial tight junctions: a promising approach to modulate intestinal barrier function

EC Rose, J Odle, AT Blikslager, AL Ziegler - International journal of …, 2021 - mdpi.com
Disruptions in the intestinal epithelial barrier can result in devastating consequences and a
multitude of disease syndromes, particularly among preterm neonates. The association …

Necrotizing enterocolitis, gut microbes, and sepsis

JW Duess, ME Sampah, CM Lopez, K Tsuboi… - Gut …, 2023 - Taylor & Francis
Necrotizing enterocolitis (NEC) is a devastating disease in premature infants and the
leading cause of death and disability from gastrointestinal disease in this vulnerable …

The compromised intestinal barrier induced by mycotoxins

Y Gao, L Meng, H Liu, J Wang, N Zheng - Toxins, 2020 - mdpi.com
Mycotoxins are fungal metabolites that occur in human foods and animal feeds, potentially
threatening human and animal health. The intestine is considered as the first barrier against …

Neonatal intestinal dysbiosis in necrotizing enterocolitis

NL Denning, JM Prince - Molecular Medicine, 2018 - Springer
Necrotizing Enterocolitis (NEC) is one of the most devastating gastrointestinal diseases in
neonates, particularly among preterm infants in whom surgical NEC is the leading cause of …

Alterations in intestinal permeability: the role of the “leaky gut” in health and disease

AS Stewart, S Pratt-Phillips, LM Gonzalez - Journal of equine veterinary …, 2017 - Elsevier
All species, including horses, suffer from alterations that increase intestinal permeability.
These alterations, also known as “leaky gut,” may lead to severe disease as the normal …

Neurodevelopmental outcome of infants who develop necrotizing enterocolitis: The gut-brain axis

J Lu, CR Martin, EC Claud - Seminars in perinatology, 2023 - Elsevier
Necrotizing enterocolitis (NEC) poses a significant risk for neurodevelopmental impairment
in extremely preterm infants. The gut microbiota shapes the development of the gut, immune …

[HTML][HTML] Targeting uPA-uPAR interaction to improve intestinal epithelial barrier integrity in inflammatory bowel disease

Y Cheng, TR Hall, X Xu, I Yung, D Souza, J Zheng… - …, 2022 - thelancet.com
Background Loss of intestinal epithelial barrier integrity is a critical component of
Inflammatory Bowel Disease (IBD) pathogenesis. Co-expression regulation of ligand …

[HTML][HTML] Role of Bifidobacterium in modulating the intestinal epithelial tight junction barrier: Current knowledge and perspectives

R Abdulqadir, J Engers, R Al-Sadi - Current Developments in Nutrition, 2023 - Elsevier
The intestinal tight junction (TJ) barrier is a crucial defense mechanism that prevents the
passage of intestinal content into the intestinal wall, tissue, and systemic circulation. A …

Anemia induces gut inflammation and injury in an animal model of preterm infants

CM Arthur, D Nalbant, HA Feldman, BJ Saeedi… - …, 2019 - Wiley Online Library
BACKGROUND While very low birth weight (VLBW) infants often require multiple red blood
cell transfusions, efforts to minimize transfusion‐associated risks have resulted in more …