The skin is the outermost layer and largest organ in the human body. Since the skin
interfaces with the environment, it has a variety of roles, including providing a protective …

Organophosphorus chlorpyrifos (CPF) is currently considered an endocrine disruptor (ED),
as it can imitate hormone actions both in vitro and in vivo. We recently reported that CPF …

The prevention of metastasis is a central goal of cancer therapy. Caveolin-1 (Cav-1) is a
structural membrane and scaffolding protein shown to be a key regulator of late-stage breast …

Aging is a major risk factor for cardiovascular diseases. Our previous studies demonstrate
that aging impairs the caveolar T‐type CaV3. 2‐RyR axis for extracellular Ca2+ influx to …

Caveolin-1 (CAV1) is a membrane-bound protein that suppresses tumor development yet
also promotes metastasis. E-cadherin is important in CAV1-dependent tumor suppression …

Metastasis is the leading cause of cancer-related deaths, making the development of novel,
more effective therapies imperative to alleviate patient suffering. Metabolic switching is a …

In prostate cancer (PCa), a characteristic stromal–epithelial redistribution of the membrane
protein caveolin 1 (CAV1) occurs upon tumor progression, where a gain of CAV1 in the …

Objective: Hydrogen sulfide (H 2 S) has been elucidated that it promotes migration and
invasion in human placenta trophoblasts. However, the signaling pathway underlying H 2 S …

Abstract Caveolin-1 (CAV1) is a membrane protein that promotes migration, invasion and
metastasis of cancer cells when phosphorylated on tyrosine-14 (Y14) by a cell intrinsic …

Daher wurde in der vorliegenden Arbeit eruiert, wie sich eine Zunahme des epithelialen
CAV1-Gehalts einerseits und der Verlust von stromalem CAV1 andererseits auf die …