Psoriasis is a systemic inflammatory disease associated with increased risk of comorbidities,
such as psoriatic arthritis, Crohn's disease, malignancy, obesity, and cardiovascular …

Tumor necrosis factor–α (TNF-α) blockers are a popular therapeutic choice in a number of
inflammatory diseases. Thus far, five TNF-α blockers have been approved for clinical use …

Treatments that block tumour necrosis factor (TNF) have major beneficial effects in several
autoimmune and rheumatic diseases, including rheumatoid arthritis. However, some …

Background Failure of anti-TNF treatment in inflammatory bowel disease (IBD) patients can
take on several forms, each posing distinct etio-pathogenic considerations and management …

AIM To investigate whether immune mediated diseases (IMD) are more frequent in patients
with inflammatory bowel disease (IBD). METHODS In this population based registry study, a …

Systemic lupus erythematosus (SLE, lupus) is characterized by a global loss of self-
tolerance with activation of autoreactive T and B cells leading to production of pathogenic …

Christopher R. Holroyd1, Rakhi Seth1, Marwan Bukhari2, Anshuman Malaviya3, Claire
Holmes1, Elizabeth Curtis4, Christopher Chan1, Mohammed A. Yusuf3, Anna Litwic4, 5 …

Background Biological therapy is currently widely used to treat IBD. Infliximab, adalimumab
and golimumab are currently licensed anti‐TNF therapies. Biosimilar anti‐TNF monoclonal …

OBJECTIVES: To analyze the clinical characteristics, outcomes, and patterns of association
with the different biologic agents used in all reported cases of adult patients developing …

Autoimmune diseases are a group of serious immune system disorders that are usually
idiopathic and persistent. Currently, autoimmune diseases are often diagnosed after obvious …