Hepatitis B virus persistence and reactivation

Y Shi, M Zheng - bmj, 2020 - bmj.com
Hepatitis B virus (HBV) infection causes chronic hepatitis and has long term complications.
Individuals ever infected with HBV are at risk of viral reactivation under certain …

Occult HBV infection

G Raimondo, T Pollicino - Hepatitis B virus in human diseases, 2016 - Springer
The long-lasting persistence of HBV genomes in the liver (and in some cases also in the
serum) of HBsAg negative subjects is termed occult HBV infection (OBI). This peculiar …

[HTML][HTML] Overview of hepatitis B virus mutations and their implications in the management of infection

P Caligiuri, R Cerruti, G Icardi… - World journal of …, 2016 - ncbi.nlm.nih.gov
Hepatitis B virus (HBV) affects approximately two billion people worldwide and more than
240 million people in the world are currently chronic carrier that could develop serious …

[HTML][HTML] Clinical implications of hepatitis B virus mutations: recent advances

I Lazarevic - World journal of gastroenterology: WJG, 2014 - ncbi.nlm.nih.gov
Hepatitis B virus (HBV) infection is a major cause of acute and chronic hepatitis, and of its
long-term complications. It is the most variable among DNA viruses, mostly because of its …

Immune-escape hepatitis B virus mutations associated with viral reactivation upon immunosuppression

I Lazarevic, A Banko, D Miljanovic, M Cupic - Viruses, 2019 - mdpi.com
Hepatitis B virus (HBV) reactivation occurs as a major complication of immunosuppressive
therapy among persons who have recovered from acute hepatitis and those who have …

[HTML][HTML] Genetic variation of occult hepatitis B virus infection

HL Zhu, X Li, J Li, ZH Zhang - World Journal of Gastroenterology, 2016 - ncbi.nlm.nih.gov
Occult hepatitis B virus infection (OBI), characterized as the persistence of hepatitis B virus
(HBV) surface antigen (HBsAg) seronegativity and low viral load in blood or liver, is a …

Anti-rheumatic drug-induced hepatitis B virus reactivation and preventive strategies for hepatocellular carcinoma

Q Zhou, Q Zhang, K Wang, T Huang, S Deng… - Pharmacological …, 2022 - Elsevier
To date, an estimated 300 million people worldwide have been infected with chronic
hepatitis B virus (HBV). Although anti-HBV therapies have improved the long-term survival …

Hepatitis B virus reactivation associated with therapeutic interventions

Y Chang, SW Jeong, JY Jang - Frontiers in Medicine, 2022 - frontiersin.org
Hepatitis B virus (HBV) reactivation associated with various therapeutic interventions is an
important cause of morbidity and mortality in patients with current or resolved HBV infection …

Occult hepatitis B virus infection and hepatocellular carcinoma: a systematic review

X Huang, FB Hollinger - Journal of viral hepatitis, 2014 - Wiley Online Library
Occult hepatitis B (OHB) infection has been reported to play an important role in the
development of hepatocellular carcinoma (HCC). In this systematic review, a significantly …

Immune-escape mutations and stop-codons in HBsAg develop in a large proportion of patients with chronic HBV infection exposed to anti-HBV drugs in Europe

L Colagrossi, LE Hermans, R Salpini, D Di Carlo… - BMC infectious …, 2018 - Springer
Background HBsAg immune-escape mutations can favor HBV-transmission also in
vaccinated individuals, promote immunosuppression-driven HBV-reactivation, and increase …