Ketamine is a dissociative anaesthetic drug which acts on the central nervous system chiefly through antagonism of the n-methyl-d-aspartate (NMDA) receptor. Recently, ketamine has …
M Pettorruso, A Miuli, K Clemente, G Mancusi… - Molecular …, 2024 - nature.com
Brain-derived neurotrophic factor (BDNF) and its precursor, proBDNF, are known to significantly contribute to brain homeostasis, neuroplasticity, and neuronal remodeling …
Background Brain-derived neurotrophic factor (BDNF) is associated with several neurodegenerative and psychiatric disorders. It is not clear, however, whether BDNF levels …
Cocaine/crack abstinence periods have higher risk of relapse. Abstinence as initial part of the recovery process is affected by learning and memory changes that could preserve the …
Rationale An important goal of addiction research is to discover neurobiological markers that could predict the severity of addiction and help to determine appropriate treatment …
NE Zlebnik, ME Carroll - Psychopharmacology, 2015 - Springer
Background Recent research has demonstrated that aerobic exercise can attenuate craving for drugs of abuse and reduce escalation and reinstatement of drug-seeking behavior in …
EG Pitts, JR Taylor, SL Gourley - Neurobiology of disease, 2016 - Elsevier
Brain-derived neurotrophic factor (BDNF) affects synaptic plasticity and neural structure and plays key roles in learning and memory processes. Recent evidence also points to …
AB Peterson, JM Abel, WJ Lynch - Psychopharmacology, 2014 - Springer
Rationale Physical activity, and specifically exercise, has shown promise as an intervention for drug addiction; however, the exercise conditions that produce the most efficacious …
J Wang, FP Deane, PJ Kelly… - Drug and Alcohol …, 2023 - Wiley Online Library
Issues Assessing drug and alcohol inpatient withdrawal treatment programs is important, as these represent a first step of treatment among people with alcohol and drug problems …