Nanocarrier‐mediated cytosolic delivery of biopharmaceuticals
Biopharmaceuticals have emerged to play a vital role in disease treatment and have shown
promise in the rapidly expanding pharmaceutical market due to their high specificity and …
promise in the rapidly expanding pharmaceutical market due to their high specificity and …
Nanomaterial designing strategies related to cell lysosome and their biomedical applications: A review
Lysosomes, an important organelle of eukaryotic cells, are covered with the cell membrane
and contain an array of degradative enzymes. The disrupt in lysosomal functions may lead …
and contain an array of degradative enzymes. The disrupt in lysosomal functions may lead …
Fluorescent Polymer Carbon Dots for the Sensitive–Selective Sensing of Fe3+ Metal Ions and Cellular Imaging
Poly (ether amine)(PEA)-based fluorescent polymer carbon dots (FPCDs) have been
synthesized via a simple Schiff base reaction between poly (ether amine)(PEA) and …
synthesized via a simple Schiff base reaction between poly (ether amine)(PEA) and …
Chemically designed nanoscale materials for controlling cellular processes
Conspectus Nanoparticles are widely used in various biomedical applications as drug
delivery carriers, imaging probes, single-molecule tracking/detection probes, artificial …
delivery carriers, imaging probes, single-molecule tracking/detection probes, artificial …
Novel approaches of dysregulating lysosome functions in cancer cells by specific drugs and its nanoformulations: a smart approach of modern therapeutics
The smart strategy of cancer cells to bypass the caspase-dependent apoptotic pathway has
led to the discovery of novel anti-cancer approaches including the targeting of lysosomes …
led to the discovery of novel anti-cancer approaches including the targeting of lysosomes …
N, S-codoped carbon dots for nontoxic cell imaging and as a sunlight-active photocatalytic material for the removal of chromium
Nitrogen–sulfur codoped carbon dots (NSCD) were synthesized via a single-step microwave-
assisted method having a fluorescence quantum yield of∼ 12%. The NSCD has been …
assisted method having a fluorescence quantum yield of∼ 12%. The NSCD has been …
Arginine Surface Density of Nanoparticles Controls Nonendocytic Cell Uptake and Autophagy Induction
Nonendocytic cell uptake of nanomaterials is challenging, which requires specific surface
chemistry and smaller particle size. Earlier works have shown that an arginine-terminated …
chemistry and smaller particle size. Earlier works have shown that an arginine-terminated …
Direct cellular delivery of exogenous genetic material and protein via colloidal nano-assemblies with biopolymer
Direct cytosolic delivery of large biomolecules that bypass the endocytic pathways is a
promising strategy for therapeutic applications. Recent works have shown that small …
promising strategy for therapeutic applications. Recent works have shown that small …
Pollutant-soot-based nontoxic water-soluble onion-like nanocarbons for cell imaging and selective sensing of toxic Cr (VI)
Presently, the technologies associated with using waste materials for the fabrication of
newer useful materials have been greatly advanced. For the same purpose, a possible …
newer useful materials have been greatly advanced. For the same purpose, a possible …
Arginine-terminated nanoparticles of< 10 nm size for direct membrane penetration and protein delivery for straight access to cytosol and nucleus
Although colloidal nanoparticles are known to enter into cells via endocytosis, the direct
membrane permeation of nanoparticles is rarely reported, and the underlying mechanism of …
membrane permeation of nanoparticles is rarely reported, and the underlying mechanism of …