[HTML][HTML] Sarcopenia in the older adult with cancer

GR Williams, RF Dunne, S Giri… - Journal of Clinical …, 2021 - ncbi.nlm.nih.gov
The term sarcopenia, derived from the Greek words sarx for flesh and penia for loss, was first
introduced by Rosenberg 1 in 1989 to describe the loss of muscle mass that accompanies …

Myosteatosis and prognosis in cancer: systematic review and meta-analysis

GFP Aleixo, SS Shachar, KA Nyrop, HB Muss… - Critical reviews in …, 2020 - Elsevier
Background The evidence that body composition parameters influence multiple cancer
outcomes is rapidly expanding. Excess adiposity deposits in muscle tissue, termed …

[HTML][HTML] Skeletal muscle cutoff values for sarcopenia diagnosis using T10 to L5 measurements in a healthy US population

BA Derstine, SA Holcombe, BE Ross, NC Wang… - Scientific reports, 2018 - nature.com
Measurements of skeletal muscle cross-sectional area, index, and radiation attenuation
utilizing clinical computed tomography (CT) scans are used in assessments of sarcopenia …

[HTML][HTML] Forcing the vicious circle: sarcopenia increases toxicity, decreases response to chemotherapy and worsens with chemotherapy

F Bozzetti - Annals of oncology, 2017 - Elsevier
Sarcopenia has recently emerged as a new condition that, independently from malnutrition,
may adversely affect the prognosis of cancer patients. Purpose of this narrative review is to …

Predictive impact of sarcopenia in solid cancers treated with immune checkpoint inhibitors: a meta‐analysis

Y Takenaka, R Oya, N Takemoto… - Journal of cachexia …, 2021 - Wiley Online Library
Sarcopenia, which is characterized by a decrease in muscle quantity or quality, is commonly
observed in patients with cancer. Recent research has reported contradictory results on the …

[HTML][HTML] Cachexia and sarcopenia in older adults with cancer: a comprehensive review

RF Dunne, KP Loh, GR Williams, A Jatoi, KM Mustian… - Cancers, 2019 - mdpi.com
Cancer cachexia is a syndrome characterized by weight loss with accompanying loss of
muscle and/or fat mass and leads to impaired patient function and physical performance and …

Muscle composition and outcomes in patients with breast cancer: meta-analysis and systematic review

GFP Aleixo, GR Williams, KA Nyrop, HB Muss… - Breast cancer research …, 2019 - Springer
Purpose Breast cancer is the most common cancer and leading cause of cancer death in
women. Body composition parameters, especially those related to muscle, have become a …

[HTML][HTML] Impact of body composition on outcomes from anti-PD1+/− anti-CTLA-4 treatment in melanoma

AC Young, HT Quach, H Song, EJ Davis… - … for ImmunoTherapy of …, 2020 - ncbi.nlm.nih.gov
Background Immune checkpoint inhibitors (ICIs) have transformed treatment for melanoma,
but identifying reliable biomarkers of response and effective modifiable lifestyle factors has …

Malnutrition in older adults with cancer

X Zhang, BJ Edwards - Current oncology reports, 2019 - Springer
Abstract Purpose of Review Malnutrition is a common and under-recognized geriatric
condition in older adults with cancer. This review describes the public health burden …

Sarcopenia & aging in cancer

GR Williams, HN Rier, A McDonald… - Journal of geriatric …, 2019 - Elsevier
Loss of skeletal muscle mass and strength is apparent as early as the 4th decade of life and
progresses linearly with increasing age [1, 2]. The term sarcopenia, first introduced by Irwin …