Adult cardiomyocytes are terminally differentiated cells that result in minimal intrinsic
potential for the heart to self-regenerate. The introduction of novel approaches in cardiac …

The falsification of data related to c-kit+ cardiac progenitor cells (CPCs) by a Harvard
laboratory has been a veritable tragedy. Does this fraud mean that CPCs are not beneficial …

Exosomes are required for the regenerative effects of human cardiosphere‐derived cells
(CDCs). Studies show that they mimic the cardioprotective benefits of CDCs in rodents and …

Purpose The aim of this study was to investigate the cardiac repair effect of human bone
marrow mesenchymal stromal cells-derived extracellular vesicles (MSC-EVs) after …

Myocardial infarction (MI) irreversibly injures the heart tissue. Cardiovascular tissue
engineering has been developed as a promising therapeutic approach for post-MI repair …

Biomaterials in conjunction with stem cell therapy have recently attracted attention as a new
therapeutic approach for myocardial infarction (MI), with the aim to solve the delivery …

Cardiovascular progenitor cells (CPCs) derived from human pluripotent stem cells (hPSCs)
are proposed to be invaluable cell sources for experimental and clinical studies. This wide …

Cardiosphere-derived cells (CDCs) have emerged as one of the most promising stem cell
types for cardiac protection and repair. Exosomes are required for the regenerative effects of …

Mounting evidence shows that cell therapy provides therapeutic benefits in experimental
and clinical settings of chronic heart failure. However, direct cardiac delivery of cells via …

Derivation of cardiomyocytes directly from patients' own fibroblasts could offer a new
therapeutic approach for those with ischemic heart disease. An essential step toward clinical …