Executive summary Traumatic brain injury (TBI) has the highest incidence of all common
neurological disorders, and poses a substantial public health burden. TBI is increasingly …

Traumatic brain injury (TBI) remains one of the most fatal and debilitating conditions in the
world. Current clinical management in severe TBI patients is mainly concerned with …

Managing traumatic brain injury (TBI) patients with a cerebral perfusion pressure (CPP) near
to the cerebral autoregulation (CA)-guided “optimal” CPP (CPPopt) value is associated with …

Impaired cerebral autoregulation (CA) in moderate/severe traumatic brain injury (TBI) has
been identified as a strong associate with poor long-term outcomes, with recent data …

Background A previous retrospective single-centre study suggested that the percentage of
time spent with cerebral perfusion pressure (CPP) below the individual lower limit of …

Intensive care for patients with traumatic brain injury (TBI) aims to optimize intracranial
pressure (ICP) and cerebral perfusion pressure (CPP). The transformation of ICP and CPP …

Introduction Multimodality monitoring of patients with severe traumatic brain injury (TBI) is
primarily performed in neuro-critical care units to prevent secondary harmful brain insults …

Traumatic brain injury (TBI) is a major public health burden, causing death and disability
worldwide. Intracranial hypertension and brain hypoxia are the main mechanisms of …

OBJECTIVE The primary aim of this study was to determine the combined effect of insult
intensity and duration of intracranial pressure (ICP), cerebral perfusion pressure (CPP), and …

Traumatic intracranial hypertension (tIH) is a common and potentially lethal complication of
moderate to severe traumatic brain injury (m-sTBI). It often develops with little warning and is …