Diagnostic classification of cancers using extreme gradient boosting algorithm and multi-omics data

B Ma, F Meng, G Yan, H Yan, B Chai, F Song - Computers in biology and …, 2020 - Elsevier
Accurate diagnostic classification of cancers can greatly help physicians to choose
surveillance and treatment strategies for patients. Following the explosive growth of huge …

Artificial intelligence in pathomics and genomics of renal cell carcinoma

JE Knudsen, JM Rich, R Ma - Urologic Clinics, 2024 - urologic.theclinics.com
Broadly defined, artificial intelligence (AI) is the ability of a computer to model some form of
human interaction. AI as a concept can be traced as far back as third-century China with the …

Machine learning for biomarker identification in cancer research–developments toward its clinical application

Z Jagga, D Gupta - Personalized medicine, 2015 - Taylor & Francis
The patterns identified from the systematically collected molecular profiles of patient tumor
samples, along with clinical metadata, can assist personalized treatments for effective …

Deep learning and radiomics: the utility of Google TensorFlow™ Inception in classifying clear cell renal cell carcinoma and oncocytoma on multiphasic CT

H Coy, K Hsieh, W Wu, MB Nagarajan, JR Young… - Abdominal …, 2019 - Springer
Purpose Currently, all solid enhancing renal masses without microscopic fat are considered
malignant until proven otherwise and there is substantial overlap in the imaging findings of …

Gene expression-based biomarkers for discriminating early and late stage of clear cell renal cancer

S Bhalla, K Chaudhary, R Kumar, M Sehgal, H Kaur… - Scientific reports, 2017 - nature.com
In this study, an attempt has been made to identify expression-based gene biomarkers that
can discriminate early and late stage of clear cell renal cell carcinoma (ccRCC) patients. We …

Prediction and analysis of skin cancer progression using genomics profiles of patients

S Bhalla, H Kaur, A Dhall, GPS Raghava - Scientific Reports, 2019 - nature.com
Abstract The metastatic Skin Cutaneous Melanoma (SKCM) has been associated with
diminished survival rates and high mortality rates worldwide. Thus, segregating metastatic …

Diagnostic classification of cancers using DNA methylation of paracancerous tissues

B Ma, B Chai, H Dong, J Qi, P Wang, T Xiong… - Scientific Reports, 2022 - nature.com
The potential role of DNA methylation from paracancerous tissues in cancer diagnosis has
not been explored until now. In this study, we built classification models using well-known …

PCA model for RNA-Seq malaria vector data classification using KNN and decision tree algorithm

MO Arowolo, M Adebiyi, A Adebiyi… - … and computer science …, 2020 - ieeexplore.ieee.org
Malaria parasites adopt unresolved discrepancy of life segments as they grow through
various mosquito vector stratospheres. Transcriptomes of thousands of individual parasites …

Computing skin cutaneous melanoma outcome from the HLA-alleles and clinical characteristics

A Dhall, S Patiyal, H Kaur, S Bhalla, C Arora… - Frontiers in …, 2020 - frontiersin.org
Human leukocyte antigen (HLA) are essential components of the immune system that
stimulate immune cells to provide protection and defense against cancer. Thousands of HLA …

ECMarker: interpretable machine learning model identifies gene expression biomarkers predicting clinical outcomes and reveals molecular mechanisms of human …

T Jin, ND Nguyen, F Talos, D Wang - Bioinformatics, 2021 - academic.oup.com
Motivation Gene expression and regulation, a key molecular mechanism driving human
disease development, remains elusive, especially at early stages. Integrating the increasing …