High-grade neuroendocrine neoplasms (HG-NENs) are clinically aggressive diseases, the
classification of which has recently been redefined. They now include both poorly …

The classification of poorly differentiated sinonasal carcinomas and their nonepithelial
mimics has experienced tremendous developments during the last 2 decades. These recent …

IDH2 R172 mutations occur in sinonasal undifferentiated carcinoma (SNUC), large-cell
neuroendocrine carcinoma (LCNEC), sinonasal adenocarcinomas, and olfactory …

The pathology of poorly differentiated sinonasal malignancies has been the subject of
extensive studies during the last decade, which resulted into significant developments in the …

Inactivating alterations in the SWItch/Sucrose NonFermentable (SWI/SNF) Chromatin
Remodeling Complex subunits have been described in multiple tumor types. Recent studies …

With wide-spread use of next generation sequencing tools in surgical pathology, a variety of
neoplasms have been increasingly recognized to be associated with specific recurrent …

Simple Summary SMARCB1 (INI-1)-deficient sinonasal carcinoma is a rare but locally
aggressive malignancy which usually presents very late with invasion into the orbits and …

Abstract Purpose of Review Sinonasal tumors are rare and heterogeneous diseases which
pose challenges in diagnosis and treatment. Despite significant progress made in surgical …

Despite the progress of surgery, radiotherapy, and neoadjuvant chemotherapy, the
prognosis for advanced sinonasal cancers (SNCs) remains poor. In the era of precision …

Aims Oncogenic FGFR1/2/3 rearrangements are found in various cancers. Reported cases
in head and neck (HN) are mainly squamous cell carcinomas (SCCs) with FGFR3:: TACC3 …