[HTML][HTML] IgG4 antibodies induced by repeated vaccination may generate immune tolerance to the SARS-CoV-2 spike protein

VN Uversky, EM Redwan, W Makis, A Rubio-Casillas - Vaccines, 2023 - mdpi.com
Less than a year after the global emergence of the coronavirus SARS-CoV-2, a novel
vaccine platform based on mRNA technology was introduced to the market. Globally, around …

Primary membranous nephropathy

WG Couser - Clinical Journal of the American Society of …, 2017 - journals.lww.com
Membranous nephropathy (MN) is a unique glomerular lesion that is the most common
cause of idiopathic nephrotic syndrome in nondiabetic white adults. About 80% of cases are …

IgG4-related disease

JH Stone, Y Zen, V Deshpande - New England Journal of …, 2012 - Mass Medical Soc
IgG4-Related Disease | New England Journal of Medicine Skip to main content The New
England Journal of Medicine homepage Advanced Search SEARCH SPECIALTIES Cardiology …

Risk HLA-DQA1 and PLA2R1 Alleles in Idiopathic Membranous Nephropathy

HC Stanescu, M Arcos-Burgos, A Medlar… - … England Journal of …, 2011 - Mass Medical Soc
Background Idiopathic membranous nephropathy is a major cause of the nephrotic
syndrome in adults, but its etiologic basis is not fully understood. We investigated the genetic …

Rituximab-induced depletion of anti-PLA2R autoantibodies predicts response in membranous nephropathy

LH Beck Jr, FC Fervenza, DM Beck… - Journal of the …, 2011 - journals.lww.com
Autoantibodies to the M-type phospholipase A 2 receptor (PLA 2 R) are sensitive and
specific for idiopathic membranous nephropathy. The anti-B cell agent rituximab is a …

Anti-phospholipase A2 receptor antibody in membranous nephropathy

W Qin, LH Beck Jr, C Zeng, Z Chen, S Li… - Journal of the …, 2011 - journals.lww.com
The M-type phospholipase A2 receptor (PLA2R) is a target autoantigen in adult idiopathic
membranous nephropathy (MN), but the prevalence of autoantibodies against PLA2R is …

Anti-phospholipase A2 receptor antibodies correlate with clinical status in idiopathic membranous nephropathy

JM Hofstra, LH Beck Jr, DM Beck… - Clinical journal of the …, 2011 - journals.lww.com
Results 77.8% of iMN patients in our cohort had antibodies reactive with human PLA 2 R.
The antibody levels in these patients correlated strongly with both clinical status and …

[HTML][HTML] Kidney disease models: tools to identify mechanisms and potential therapeutic targets

YW Bao, Y Yuan, JH Chen, WQ Lin - Zoological research, 2018 - ncbi.nlm.nih.gov
Acute kidney injury (AKI) and chronic kidney disease (CKD) are worldwide public health
problems affecting millions of people and have rapidly increased in prevalence in recent …

PLA2R Autoantibodies and PLA2R Glomerular Deposits in Membranous Nephropathy

H Debiec, P Ronco - New England Journal of Medicine, 2011 - Mass Medical Soc
To the Editor: Membranous nephropathy is a common cause of the nephrotic syndrome in
adults. Treatment is controversial and challenging because of the heterogeneity of the …

Glomerular diseases: membranous nephropathy—a modern view

C Ponticelli, RJ Glassock - … Journal of the American Society of …, 2014 - journals.lww.com
Membranous nephropathy (MN) is an autoimmune disease usually associated with a
nephrotic syndrome and it may progress to ESRD in the long term. Its etiology is often …