As the field of translational 'omics has progressed, refined classifiers at both genomic and
proteomic levels have emerged to decipher the heterogeneity of breast cancer in a clinically …

Although treatment with taxanes does not always lead to clinical benefit, all patients are at
risk of their detrimental side effects such as peripheral neuropathy. Understanding the in …

Single-cell sequencing technology provides apparent advantages in cell population
heterogeneity, allowing individuals to better comprehend tissues and organs. Sequencing …

Background Hyperthermic intraperitoneal chemotherapy (HIPEC) improves survival in
patients with Stage III ovarian cancer following interval cytoreductive surgery (CRS) …

Purpose: To explore the clinical significance of copper-dependent-related genes (CDRG) in
female breast cancer (BC). Methods: CDRG were obtained by single-cell analysis of the …

BACKGROUND The association between tumor-infiltrating lymphocyte (TIL) levels and the
response to neoadjuvant therapy (NAT) in patients with triple-negative breast cancer (TNBC) …

This study aimed to explore the roles of radiotherapy-sensitive and ferroptosis genes in
breast cancer (BRCA). Genes differentially expressed pre-and post-radiotherapy from the …

Recent advancements in single-cell RNA sequencing (scRNA-seq) have enabled the
identification of phenotypic diversity within breast tumor tissues. However, the contribution of …

Despite thorough characterizations of cellular compositions within the breast tumor
microenvironment (TME), their implications for disease progression and patient prognosis …

The tumor microenvironment (TME) is a complex ecosystem of diverse cell types whose
interactions govern tumor growth and clinical outcome. While the TME's impact on …