Taurine as a natural antioxidant: From direct antioxidant effects to protective action in various toxicological models

PF Surai, K Earle-Payne, MT Kidd - Antioxidants, 2021 - mdpi.com
Natural antioxidants have received tremendous attention over the last 3 decades. At the
same time, the attitude to free radicals is slowly changing, and their signalling role in …

Significance of taurine transporter (TauT) in homeostasis and its layers of regulation

S Baliou, AM Kyriakopoulos… - Molecular …, 2020 - spandidos-publications.com
Abstract Taurine (2‑aminoethanesulfonic acid) contributes to homeostasis, mainly through
its antioxidant and osmoregulatory properties. Taurine's influx and efflux are mainly …

Hepatorenal protective effects of taurine and N-acetylcysteine against fipronil-induced injuries: the antioxidant status and apoptotic markers expression in rats

MM Abdel-Daim, AA Dessouki… - Science of the total …, 2019 - Elsevier
Fipronil (FPN), a commonly used phenylpyrazole pesticide can induce oxidative tissue
damage following hazard usage. Due to the extensive household and commercial usage of …

In vivo toxicity of poly(propyleneimine) dendrimers

B Ziemba, A Janaszewska, K Ciepluch… - … Research Part A, 2011 - Wiley Online Library
Dendrimers are highly branched macromolecules with the potential to be used for
biomedical applications. Several dendrimers are toxic owing to their positively charged …

Role of taurine, its haloamines and its lncRNA TUG1 in both inflammation and cancer progression. On the road to therapeutics?

S Baliou, AM Kyriakopoulos… - International …, 2020 - spandidos-publications.com
For one century, taurine is considered as an end product of sulfur metabolism. In this review,
we discuss the beneficial effect of taurine, its haloamines and taurine upregulated gene 1 …

The footprints of mitochondrial impairment and cellular energy crisis in the pathogenesis of xenobiotics-induced nephrotoxicity, serum electrolytes imbalance, and …

R Heidari - Toxicology, 2019 - Elsevier
Fanconi's Syndrome (FS) is a disorder characterized by impaired renal proximal tubule
function. FS is associated with a vast defect in the renal reabsorption of several chemicals …

Cisplatin-Induced Kidney Toxicity: Potential Roles of Major NAD+-Dependent Enzymes and Plant-Derived Natural Products

A Iskander, LJ Yan - Biomolecules, 2022 - mdpi.com
Cisplatin is an FDA approved anti-cancer drug that is widely used for the treatment of a
variety of solid tumors. However, the severe adverse effects of cisplatin, particularly kidney …

Synergistic protective effect of N-acetylcysteine and taurine against cisplatin-induced nephrotoxicity in rats

WM Abdel-Wahab, FI Moussa… - Drug design, development …, 2017 - Taylor & Francis
Cisplatin (cis-diaminedichloroplatinum II; CDDP) is an effective anticancer drug, but it has
limitations because of its nephrotoxicity. This study investigates the protective effect of N …

Cellular and mitochondrial taurine depletion in bile duct ligated rats: a justification for taurine supplementation in cholestasis/cirrhosis

A Najibi, H Rezaei, RK Manthari, H Niknahad… - Clinical and …, 2022 - termedia.pl
Taurine (TAU) is a free amino acid abundant in the human body. Various physiological roles
have been attributed to TAU. At the subcellular level, mitochondria are the primary targets for …

[HTML][HTML] Sulfasalazine-induced renal and hepatic injury in rats and the protective role of taurine

R Heidari, M Rasti, BS Yeganeh, H Niknahad… - BioImpacts …, 2016 - ncbi.nlm.nih.gov
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Introduction: Sulfasalazine is a drug commonly administrated against inflammatory-based …