Protein therapeutics hold a prominent and rapidly expanding place among medicinal
products. Purified blood products, recombinant cytokines, growth factors, enzyme …

Macromolecular structures, such as neuraminidases, hemagglutinins, and monoclonal
antibodies, are not rigid entities. Rather, they are characterised by their flexibility, which is …

It has recently become possible to simultaneously assay T‐cell specificity with respect to
large sets of antigens and the T‐cell receptor sequence in high‐throughput single‐cell …

Epitope-based DNA vaccine development is one application of bioinformatics or in silico
studies, that is, computational methods, including mathematical, chemical, and biological …

Protein-protein interactions govern a wide range of biological activity. A proper estimation of
the protein-protein binding affinity is vital to design proteins with high specificity and binding …

Understanding the mechanisms involved in the activation of an immune response is
essential to many fields in human health, including vaccine development and personalized …

A large volume of data relevant to immunology research has accumulated due to
sequencing of genomes of the human and other model organisms. At the same time, huge …

The interaction between T-cell receptors (TCRs) and major histocompatibility complex
(MHC)-bound epitopes is one of the most important processes in the adaptive human …

Abstract Excepting the Peripheral and Central Nervous Systems, the Immune System is the
most complex of somatic systems in higher animals. This complexity manifests itself at many …

Peptides fulfill many roles in immunology, yet none are more important than their role as
immunogenic epitopes driving the adaptive immune response, our ultimate bulwark against …