Identifying causal associations between women's reproductive traits and risk of schizophrenia: a multivariate validated two-sample Mendelian randomization analysis

W Sun, X Wu, H Yang, S Yuan, J Chen, Y Fang… - BMC psychiatry, 2024 - Springer
Background A significant association between women's reproductive traits and the risk of
schizophrenia (SCZ) has been discovered, but the causalities remain unclear. We designed …

Mendelian randomization analyses for the causal relationship between early age at first sexual intercourse, early age at first live birth, and postpartum depression in …

X Zhao, L Liu - Frontiers in Psychiatry, 2024 - frontiersin.org
Introduction There are insufficient epidemiological studies on the impact of age at first sexual
intercourse (AFS) and age at first live birth (AFB) on postpartum depression (PPD) in …

Fitness consequences of depressive symptoms vary between generations: Evidence from a large cohort of women across the 20th century

CI Gurguis, RA Duckworth, NM Bucaro, C Walss-Bass - Plos one, 2024 - journals.plos.org
Depression has strong negative impacts on how individuals function, leading to the
assumption that there is strong negative selection on this trait that should deplete genetic …

Common mental disorders and risk of female infertility: a two-sample Mendelian randomization study

D Mao, M Lin, R Li - Frontiers in Endocrinology, 2024 - frontiersin.org
Introduction Female infertility is a global issue that impacts on public health seriously and
many mental disorders are observed in infertility groups. Methods To investigate the casual …

Causal effects of potential risk factors on postpartum depression: a Mendelian randomization study

M Zuo, Z Wang, W Li, S Chen, Y Yuan, Y Yang… - Frontiers in …, 2023 - frontiersin.org
Background Postpartum depression (PPD) is a type of depressive episode related to parents
after childbirth, which causes a variety of symptoms not only for parents but also affects the …

Early sexual activity lowers the incidence of intracranial aneurysm: a Mendelian randomization investigation

P Wu, P Akram, K Kadeer, M Aisha, X Cheng… - Frontiers in …, 2024 - frontiersin.org
Objective Investigate the potential correlation between the age of initial sexual contact, the
lifetime accumulation of sexual partners, and the occurrence of intracranial aneurysm (IA) …

Health condition and socioeconomic status mediate the causal effect of reproductive traits on nonalcoholic fatty liver disease: evidence from Mendelian randomization …

Q Wang, L Wang, R Hao, L Zhang, W Wang… - Frontiers in …, 2024 - frontiersin.org
Background Observational data posits a correlation between reproductive traits and
nonalcoholic fatty liver disease (NAFLD), but their causal inference is still unclear. This …

Investigating the Mediating Role of Mental Disorders in the Relationship Between Early Sexual Intercourse and Intentional Self‐Harm: A Two‐Step and Multivariable …

D Dong, S Saeed, R Chen, A Chen… - Brain and …, 2024 - Wiley Online Library
Background Epidemiological studies have established an association between early sexual
intercourse and intentional self‐harm. However, the causal mechanisms, particularly the role …

Causal relationship between Women's reproductive traits and postpartum depression: a multivariate mendelian randomization analysis

Z Kang, Q Wu, J Cao, M Zhu, Z You, D Li… - Frontiers in Genetics, 2024 - frontiersin.org
Purpose The relationship between women's reproductive traits and postpartum depression
(PPD) has not been clarified. We reveal the association between genetically predicted …

The causal relationships between early sexual behaviors and cancer risks in individuals of European ancestry: a two-step Mendelian randomization study

P Xue, J Dai, B Kuai, X Su, Y Shi, Y Guo - 2023 - researchsquare.com
Background Sexual behaviors have been found to be linked to a variety of cancer risks.
While The association between early sexual behaviors and cancer risk, as well as its …