Lipid-based nanoparticles: application and recent advances in cancer treatment

B García-Pinel, C Porras-Alcalá, A Ortega-Rodríguez… - Nanomaterials, 2019 - mdpi.com
Many therapeutically active molecules are non-soluble in aqueous systems, chemically and
biologically fragile or present severe side effects. Lipid-based nanoparticle (LBNP) systems …

Lipid-based nanoparticles as a pivotal delivery approach in triple negative breast cancer (TNBC) therapy

A Chaudhuri, DN Kumar, RA Shaik, BG Eid… - International journal of …, 2022 - mdpi.com
Triple-negative breast cancer is considered the most aggressive type of breast cancer
among women and the lack of expressed receptors has made treatment options …

Targeting NF-κB signaling pathway in cancer by dietary polyphenols

H Khan, H Ullah, PCMF Castilho… - Critical Reviews in …, 2020 - Taylor & Francis
Being a transcription factor, NF-κB regulates gene expressions involving cell survival and
proliferation, drug resistance, metastasis, and angiogenesis. The activation of NF-κB plays a …

Bioactive compounds: natural defense against cancer?

S Subramaniam, KR Selvaduray, AK Radhakrishnan - Biomolecules, 2019 - mdpi.com
Cancer is a devastating disease that has claimed many lives. Natural bioactive agents from
plants are gaining wide attention for their anticancer activities. Several studies have found …

Mechanism insights of curcumin and its analogues in cancer: An update

P Joshi, K Verma, D Kumar Semwal… - Phytotherapy …, 2023 - Wiley Online Library
Cancer is the world's second leading cause of mortality and one of the major public health
problems. Cancer incidence and mortality rates remain high despite the great …

In vitro assays and techniques utilized in anticancer drug discovery

MK Ediriweera, KH Tennekoon… - Journal of Applied …, 2019 - Wiley Online Library
Abstract Development of a cancer is a multistep process and six major hallmarks of cancer
that are known to control malignant transformation have been described. Anticancer drug …

Targeting oncogenic transcription factors by polyphenols: A novel approach for cancer therapy

C Rajagopal, MB Lankadasari, JM Aranjani… - Pharmacological …, 2018 - Elsevier
Inflammation is one of the major causative factor of cancer and chronic inflammation is
involved in all the major steps of cancer initiation, progression metastasis and drug …

Cancer chemoprevention by phytochemicals: Nature's healing touch

H Zubair, S Azim, A Ahmad, MA Khan, GK Patel… - Molecules, 2017 - mdpi.com
Phytochemicals are an important part of traditional medicine and have been investigated in
detail for possible inclusion in modern medicine as well. These compounds often serve as …

Recent advances in liposome-based targeted cancer therapy

Y Fidan, S Muçaj, SS Timur… - Journal of Liposome …, 2024 - Taylor & Francis
Nano-drug delivery systems have opened new pathways for tumor treatment by overcoming
some of the limitations of conventional drugs, such as physiological degradation, short half …

Bioactivities of EF24, a novel curcumin analog: a review

Y He, W Li, G Hu, H Sun, Q Kong - Frontiers in Oncology, 2018 - frontiersin.org
Curcumin is an attractive agent due to its multiple bioactivities. However, the low oral
bioavailability and efficacy profile hinders its clinical application. To improve the …