Immunoregulation by mesenchymal stem cells: biological aspects and clinical applications

ME Castro-Manrreza… - Journal of immunology …, 2015 - Wiley Online Library
Mesenchymal stem cells (MSCs) are multipotent cells capable of differentiation into
mesenchymal lineages and that can be isolated from various tissues and easily cultivated in …

TNF-α and IFN-γ participate in improving the immunoregulatory capacity of mesenchymal stem/stromal cells: Importance of cell–cell contact and extracellular vesicles

L López-García, ME Castro-Manrreza - International journal of molecular …, 2021 - mdpi.com
Mesenchymal stem/stromal cells (MSCs) have an immunoregulatory capacity and have
been used in different clinical protocols requiring control of the immune response. However …

Comparing the immunomodulatory properties of bone marrow, adipose tissue, and birth-associated tissue mesenchymal stromal cells

P Mattar, K Bieback - Frontiers in immunology, 2015 - frontiersin.org
Mesenchymal stromal cells (MSC) have gained immense attraction in regenerative
medicine, tissue engineering, and immunotherapy. This is based on their differentiation …

Mesenchymal stromal cells and immunomodulation: a gathering of regulatory immune cells

M Najar, G Raicevic, H Fayyad-Kazan, D Bron… - Cytotherapy, 2016 - Elsevier
Because of their well-recognized immunomodulatory properties, mesenchymal stromal cells
(MSCs) represent an attractive cell population for therapeutic purposes. In particular, there is …

Double‐edged sword of mesenchymal stem cells: cancer‐promoting versus therapeutic potential

HY Lee, IS Hong - Cancer science, 2017 - Wiley Online Library
Mesenchymal stem cells (MSCs) derived from adipose tissue, bone marrow, cord blood, and
other tissues, have recently attracted much attention as potential therapeutic agents in …

Human umbilical cord mesenchymal stem cells: an overview of their potential in cell-based therapy

T Li, M Xia, Y Gao, Y Chen, Y Xu - Expert opinion on biological …, 2015 - Taylor & Francis
Introduction: Human umbilical cord mesenchymal stem cells (HUC-MSCs) are one of the
typical adult stem cells; they have superiorities including low immunogenicity, non-invasive …

Chronic niche inflammation in endometriosis-associated infertility: current understanding and future therapeutic strategies

YH Lin, YH Chen, HY Chang, HK Au, CR Tzeng… - International journal of …, 2018 - mdpi.com
Endometriosis is an estrogen-dependent inflammatory disease that affects up to 10% of
women of reproductive age and accounts for up to 50% of female infertility cases. It has …

Mechanisms of T‐cell immunosuppression by mesenchymal stromal cells: What do we know so far?

R Haddad, F Saldanha-Araujo - BioMed research international, 2014 - Wiley Online Library
Mesenchymal stromal cells (MSCs) are multipotent cells, which can give rise to several cell
types including osteoblasts, adipocytes, and chondroblasts. These cells can be found in a …

Systematic review and meta-analysis of cell therapy for COVID-19: global clinical trial landscape, published safety/efficacy outcomes, cell product manufacturing and …

PS Couto, N Al-Arawe, IS Filgueiras… - Frontiers in …, 2023 - frontiersin.org
During the pandemic of severe respiratory distress syndrome coronavirus 2 (SARS-CoV2),
many novel therapeutic modalities to treat Coronavirus 2019 induced disease (COVID-19) …

Coordinated metabolic transitions and gene expression by NAD+ during adipogenesis

E Sánchez-Ramírez, TPL Ung… - Journal of Cell …, 2022 - rupress.org
Adipocytes are the main cell type in adipose tissue, which is a critical regulator of
metabolism, highly specialized in storing energy as fat. Adipocytes differentiate from …