The granulosa cell (GC) is a critical somatic component of the ovary. It is essential for follicle
development by supporting the developing oocyte, proliferating and producing sex steroids …

Most of the mammalian follicles undergo a degenerative process called “follicle atresia”.
Apoptosis of granulosa cells is the main characteristic of follicle atresia. Follicle stimulating …

Follicle-stimulating hormone receptor (FSHR) and its intracellular signaling control
mammalian follicular development and female infertility. Our previous study showed that …

Background Ovarian follicle development plays an important role in determination of poultry
egg production. The follicles at the various developmental stages possess their own distinct …

Due to the fact that modern American and European women postpone childbirth until later in
life, they are more likely to face the problem of ovarian insufficiency by the time they are …

STUDY QUESTION Can novel genetic candidates involved in follicle dormancy, activation
and integrity be identified from transcriptomic profiles of isolated granulosa cells from human …

Radiotherapy is a well-known cause of premature ovarian failure (POF). Therefore, we
investigated the molecular influence of genistein (GEN) on the ovarian reserve of rats …

The majority of activated ovarian follicles undergo atresia during reproductive life in
mammals, and only a small number of follicles are ovulated. Though hormone treatment has …

The SLIT2 ligand and ROBO receptors of the SLIT/ROBO pathway are expressed in hen
ovarian follicles and have been shown to play critical roles in ovary development, cell …

The Hippo/MST signaling pathway is a critical player in controlling cell proliferation, self-
renewal, differentiation, and apoptosis of most tissues and organs in diverse species …