Diabetic kidney disease is the leading cause of kidney failure worldwide; in the USA, it
accounts for over 50% of individuals entering dialysis or transplant programmes. Unlike …

Chronic kidney disease (CKD) is a devastating condition that is reaching epidemic levels
owing to the increasing prevalence of diabetes mellitus, hypertension and obesity, as well …

Autophagy is a conserved lysosomal pathway for the degradation of cytoplasmic
components. Basal autophagy in kidney cells is essential for the maintenance of kidney …

Globally, the incidence and prevalence of diabetes mellitus has risen dramatically, owing
mainly to the increase in type 2 diabetes mellitus (T2DM). In 2021, 537 million people …

Based on global estimates, almost 10% of adults have diabetes, of whom 40% are estimated
to also have chronic kidney disease (CKD). Almost 2 decades ago, treatments targeting the …

Cardiovascular disease and infections are major causes for the high incidence of morbidity
and mortality of patients with chronic kidney disease. Both complications are directly or …

SARS-CoV-2 causes a severe pneumonia (COVID-19) that affects essentially elderly
people. In COVID-19, macrophage infiltration into the lung causes a rapid and intense …

A growing body of evidence points to the role of glucose variability (GV) in the development
of the microvascular and macrovascular complications of diabetes. In this review, we …

Autophagy is a self‐digestive process that degrades intracellular components, including
damaged organelles, to maintain energy homeostasis and to cope with cellular stress …

Diabetic nephropathy is a common complication of type I and type II diabetes, in which renal
glomeruli are destroyed, resulting in renal damage, proteinuria, and hypertension …