Abstract MicroRNA-1 (miR-1) is a conserved miRNA with high expression in the muscle
tissues. In humans, two discrete genes, MIRN1-1 and MIRN1-2 residing on a genomic …

Tumor-associated macrophages (TAMs) are among the abundant cell populations of the
tumor microenvironment (TME), which have pivotal roles in tumor development …

Converging evidence demonstrates that microRNAs (miRNAs) play an important role in the
etiology of cognitive impairment. Thus, we aim to:(i) identify the molecular mechanisms of …

Background In cancer progression, hypoxia, or low oxygen tension, is a major regulator of
tumor aggressiveness and metastasis. However, how cancer cells adapt to the hypoxia and …

MicroRNAs play key roles during various crucial cell processes, such as proliferation,
migration, and invasion. In addition, microRNAs have been shown to possess oncogenic …

Bladder cancer (BlCa) is a highly immunogenic cancer. Bacillus Calmette-Guérin (BCG) is
the standard treatment for non-muscle invasive bladder cancer (NMIBC) patients and …

MicroRNAs (miRNAs) are transcripts with sizes of about 22 nucleotides, which are produced
through a multistep process in the nucleus and cytoplasm. These transcripts modulate the …

Bladder cancer is a very common malignancy. Although new treatment strategies have been
developed, the identification of new therapeutic targets and reliable diagnostic/prognostic …

Cancer is a malignant tumor that seriously threatens human life and health. At present, the
main treatment methods include surgical resection, chemotherapy, radiotherapy, and …

Osteoporosis (OP) is a systemic skeletal disorder with the characteristics of bone mass
reduction and microarchitecture deterioration, resulting in bone fragility and increased …