Inflammatory bowel disease (IBD) affects 6.8 million people globally. A variety of factors
have been implicated in IBD pathogenesis, including host genetics, immune dysregulation …

Simple and complex carbohydrates (glycans) have long been known to play major
metabolic, structural and physical roles in biological systems. Targeted microbial binding to …

Signalling C‐type lectin receptors (CLR s) are crucial in shaping the immune response to
fungal pathogens, but comparably little is known about the role of these receptors in …

In the last decade, glycan microarrays have revolutionized the analysis of the specificity of
glycan-binding proteins (GBPs), providing information that simultaneously illuminates the …

Glycosylation is one of the major posttranslational modifications of proteins. N‐glycosylation
(Asn‐linked) and O‐glycosylation (Ser/Thr‐linked) are the two main forms. Abnormal O …

Through their specific interactions with proteins, cellular glycans play key roles in a wide
range of physiological and pathological processes. One of the main goals of research in the …

C-type lectins expressed on myeloid cells comprise a family of proteins that share a common
structural motif, and some act as receptors in pathogen recognition. But just as the presence …

Mononuclear phagocytes often function as control switches of the immune system, securing
the balance between pro-and anti-inflammatory reactions. For this purpose and depending …

Abstract Information contained in the mammalian glycome is decoded by glycan-binding
proteins (GBPs) that mediate diverse functions including host-pathogen interactions, cell …

Dendritic cells (DCs) are well-established as major players in the regulation of immune
responses. They either induce inflammatory or tolerogenic responses, depending on the DC …