Helminth parasites infect almost one-third of the world's population, primarily in tropical
regions. However, regions where helminth parasites are endemic record much lower …

Fibrosis is the production of excessive amounts of connective tissue, ie, scar formation, in
the course of reactive and reparative processes. Fibrosis develops as a consequence of …

There is a wealth of immunologic studies that have been carried out in experimental and
human schistosomiasis that can be classified into three main areas: immunopathogenesis …

Inflammation plays a role in the pathogenesis of acute-on-chronic liver failure (ACLF),
however, whether there is a causal relationship between inflammation and ACLF remains …

Schistosomiasis continues to be a significant cause of parasitic morbidity and mortality
worldwide. This review considers the basic features of the pathology and clinical outcomes …

Schistosomiasis treatment relies on the use of a single drug, praziquantel, which is
insufficient to control transmission in highly endemic areas. Novel medicines and vaccines …

Fibrosis is an important health problem, and its pathogenetic principles are still largely
unknown. It can develop either spontaneously, or, more frequently, as a consequence of …

Schistosomiasis is a tropical parasitic disease caused by blood-dwelling fluke worms of the
genus Schistosoma whose infective stages, the cercariae, are amplified through mollusks …

Parasitological detection of Schistosoma is the cornerstone of schistosomiasis diagnosis in
areas of transmission worldwide. However, a steep decrease of sensitivity in low-endemicity …

Fibrogenesis is a common feature of many diseases where there is severe insult to the liver.
The hepatic stellate cell trans-differentiation into a myofibroblast has been identified as an …