Porphyrinoid biohybrid materials as an emerging toolbox for biomedical light management

V Almeida-Marrero, E van de Winckel… - Chemical Society …, 2018 - pubs.rsc.org
The development of photoactive and biocompatible nanomaterials is a current major
challenge of materials science and nanotechnology, as they will contribute to promoting …

Fluorescent amino acids as versatile building blocks for chemical biology

Z Cheng, E Kuru, A Sachdeva, M Vendrell - Nature Reviews Chemistry, 2020 - nature.com
Fluorophores have transformed the way we study biological systems, enabling non-invasive
studies in cells and intact organisms, which increase our understanding of complex …

A functional chemiluminescent probe for in vivo imaging of natural killer cell activity against tumours

JI Scott, S Gutkin, O Green… - Angewandte Chemie …, 2021 - Wiley Online Library
Natural killer (NK) cells are immune cells that can kill certain types of cancer cells. Adoptive
transfer of NK cells represents a promising immunotherapy for malignant tumours; however …

[HTML][HTML] Extracellular vesicles derived from apoptotic cells: an essential link between death and regeneration

M Li, L Liao, W Tian - Frontiers in cell and developmental biology, 2020 - frontiersin.org
Apoptosis is a universal and continuous event during tissue development, restoration,
repair, and regeneration. Mounting evidence has demonstrated that apoptosis is essential …

Near-infrared fluorescent probes for the detection of cancer-associated proteases

JI Scott, Q Deng, M Vendrell - ACS chemical biology, 2021 - ACS Publications
Proteases are enzymes capable of catalyzing protein breakdown, which is critical across
many biological processes. There are several families of proteases, each of which perform …

Small Fluorogenic Amino Acids for Peptide‐Guided Background‐Free Imaging

F De Moliner, Z Konieczna… - Angewandte Chemie …, 2023 - Wiley Online Library
The multiple applications of super‐resolution microscopy have prompted the need for
minimally invasive labeling strategies for peptide‐guided fluorescence imaging. Many …

Late‐Stage Peptide Diversification through Cobalt‐Catalyzed C− H Activation: Sequential Multicatalysis for Stapled Peptides

MM Lorion, N Kaplaneris, J Son, R Kuniyil… - Angewandte …, 2019 - Wiley Online Library
Bioorthogonal late‐stage diversification of structurally complex peptides has enormous
potential for drug discovery and molecular imaging. In recent years, transition‐metal …

SCOTfluors: small, conjugatable, orthogonal, and tunable fluorophores for in vivo imaging of cell metabolism

S Benson, A Fernandez, ND Barth… - Angewandte …, 2019 - Wiley Online Library
The transport and trafficking of metabolites are critical for the correct functioning of live cells.
However, in situ metabolic imaging studies are hampered by the lack of fluorescent …

Nonperturbative fluorogenic labeling of immunophilins enables the wash-free detection of immunosuppressants

M Bertolini, L Mendive-Tapia, O Ghashghaei… - ACS Central …, 2024 - ACS Publications
Immunosuppressants are clinically approved drugs to treat the potential rejection of
transplanted organs and require frequent monitoring due to their narrow therapeutic …

Miniaturized chemical tags for optical imaging

S Benson, F De Moliner, W Tipping… - Angewandte Chemie …, 2022 - Wiley Online Library
Recent advances in optical bioimaging have prompted the need for minimal chemical
reporters that can retain the molecular recognition properties and activity profiles of …