Donor-specific antibodies in kidney transplant recipients

R Zhang - Clinical Journal of the American Society of Nephrology, 2018 - journals.lww.com
Donor-specific antibodies have become an established biomarker predicting antibody-
mediated rejection. Antibody-mediated rejection is the leading cause of graft loss after …

The therapeutic challenge of late antibody‐mediated kidney allograft rejection

GA Böhmig, F Eskandary, K Doberer… - Transplant …, 2019 - Wiley Online Library
Late antibody‐mediated rejection (ABMR) is a cardinal cause of kidney allograft failure,
manifesting as a continuous and, in contrast with early rejection, often clinically silent …

Torque Teno virus load—inverse association with antibody-mediated rejection after kidney transplantation

M Schiemann, E Puchhammer-Stöckl… - …, 2017 - journals.lww.com
Background Antibody-mediated rejection (AMR) represents one of the cardinal causes of
late allograft loss after kidney transplantation, and there is great need for noninvasive tools …

[HTML][HTML] Anti-C1s monoclonal antibody BIVV009 in late antibody-mediated kidney allograft rejection—results from a first-in-patient phase 1 trial

F Eskandary, B Jilma, J Mühlbacher… - American Journal of …, 2018 - Elsevier
The classical pathway (CP) of complement may contribute to the pathogenesis of antibody-
mediated rejection (ABMR). Selective CP blockade may be a promising strategy to …

Transcript engineered extracellular vesicles alleviate alloreactive dynamics in renal transplantation

J Lin, J Lv, S Yu, Y Chen, H Wang, J Chen - Advanced Science, 2022 - Wiley Online Library
Direct contact of membrane molecules and cytokine interactions orchestrate immune
homeostasis. However, overcoming the threshold of distance and velocity barriers, and …

Acute antibody-mediated rejection in kidney transplant recipients

S Davis, JE Cooper - Transplantation reviews, 2017 - Elsevier
Antibody-mediated rejection has now been recognized as one of the most important causes
of graft loss. Transplantation across HLA barriers and nonadherence can result in acute …

Diagnostic contribution of donor-specific antibody characteristics to uncover late silent antibody-mediated rejection—results of a cross-sectional screening study

F Eskandary, G Bond, N Kozakowski, H Regele… - …, 2017 - journals.lww.com
Background Circulating donor-specific antibodies (DSA) detected on bead arrays may not
inevitably indicate ongoing antibody-mediated rejection (AMR). Here, we investigated …

The role of the mesangium in glomerular function

R Boi, K Ebefors, J Nyström - Acta Physiologica, 2023 - Wiley Online Library
When discussing glomerular function, one cell type is often left out, the mesangial cell (MC),
probably since it is not a part of the filtration barrier per se. The MCs are instead found …

[HTML][HTML] The role of C4d deposition in the diagnosis of antibody-mediated rejection after lung transplantation

PR Aguilar, D Carpenter, J Ritter, RD Yusen… - American Journal of …, 2018 - Elsevier
Antibody-mediated rejection (AMR) is an increasingly recognized form of lung rejection. C4d
deposition has been an inconsistent finding in previous reports and its role in the diagnosis …

[HTML][HTML] Molecular assessment of C4d-positive renal transplant biopsies without evidence of rejection

KM Dominy, M Willicombe, T Al Johani… - Kidney international …, 2019 - Elsevier
Introduction Immunohistochemical staining for C4d in peritubular capillaries has been part of
antibody-mediated rejection (AbMR) definition in the Banff Classification for Allograft …