After a century of false hopes, recent studies have placed the concept of diaschisis at the
centre of the understanding of brain function. Originally, the term 'diaschisis' was coined by …

Connections between neurons are affected within 3 min of stroke onset by massive ischemic
depolarization and then delayed cell death. Some connections can recover with prompt …

Sensory hypersensitivity is a common symptom in autism spectrum disorders (ASDs),
including fragile X syndrome (FXS), and frequently leads to tactile defensiveness. In mouse …

Metformin is currently the first‐line treatment drug for type 2 diabetes. Metformin is a well‐
known activator of AMP‐activated protein kinase (AMPK). In experimental studies, metformin …

Recent human neuroimaging studies indicate that spontaneous fluctuations in neural
activity, as measured by functional connectivity magnetic resonance imaging (fcMRI), are …

To regain sensorimotor functions after stroke, surviving neural circuits must reorganize and
form new connections. Although the thalamus is critical for processing and relaying sensory …

Neural circuits, such as synaptic plasticity and neural activity, are critical components of
healthy brain function. The consequent dynamic remodeling of neural circuits is an ongoing …

Dendritic spines are ubiquitous postsynaptic sites of most excitatory synapses in the
mammalian brain, and thus may serve as structural indicators of functional synapses …

Rehabilitation is considered the most effective treatment for promoting the recovery of motor
deficits after stroke. One of the most challenging experimental goals is to unambiguously link …

Recovery after stroke is thought to be mediated by adaptive circuit plasticity, whereby
surviving neurons assume the roles of those that died. However, definitive longitudinal …