Targeted nanotheranostic systems offer significant benefits due to the integration of
diagnostic and therapeutic functionality, promoting personalized medicine. In recent years …

The independence of research is a key strategic issue of modern societies. Dealing with it
appropriately poses legal, economic, political, social and cultural problems for society, which …

While problems with cell line misidentification have been known for decades, an unknown
number of published papers remains in circulation reporting on the wrong cells without …

A variety of microscopy techniques are used by researchers in the life and biomedical
sciences. As these techniques become more powerful and more complex, it is vital that …

Cell lines are commonly used as cancer models. The tissue of origin provides context for
understanding biological mechanisms and predicting therapy response. We therefore …

Oral squamous cell carcinoma (OSCC) has a high recurrence rate and poor prognosis.
Hispolon, a polyphenolic compound with antiviral, antioxidant, and anticancer activities, is a …

The earliest mammalian cell lines, established by Earle et al. in 1943, were derived from the
subcutaneous tissue of a C3H mouse strain and many cell lines still used today were …

Folate receptors including folate receptor α (FRα) are overexpressed in up to 90% of ovarian
cancers. Ovarian cancers overexpressing FRα often exhibit high degrees of drug resistance …

Metallodrugs were classically screened against skin cancer (either in vitro or in vivo) at the
peak of the development of platinum anticancer agents. New systematic studies appeared in …

Marine sponge-derived manoalide has a potent anti-inflammatory effect, but its potential
application as an anti-cancer drug has not yet been extensively investigated. The purpose of …