Complex biological processes such as embryogenesis require precise coordination of cell
differentiation programs across both space and time. Using protein-fusion fluorescent …

Targeting of inner nuclear membrane (INM) proteins is essential for nuclear architecture and
function, yet its mechanism remains poorly understood. Here, we established a new reporter …

A confocal laser scanning microscope (CLSM) enables us to capture images from a
biological specimen in different depths and obtain a series of precisely registered …

Elucidating the expression of microRNAs in developing single cells is critical for functional
discovery. Here, we construct scCAMERA (single-cell cartography of microRNA expression …

The advent of genome-wide RNA interference (RNAi)–based screens puts us in the position
to identify genes for all functions human cells carry out. However, for many functions, assay …

In fleshy fruits, the variability of cell morphology at the fruit scale is largely unknown. It
presents both a huge variability and a high level of organization. Better knowledge of cell …

During cellular morphogenesis, changes in cell shape and cell junction topology are
fundamental to normal tissue and organ development. Here we show that apoplastic …

Confocal laser scanning microscopy (CLSM) is one of the most relevant technologies for
studying biofilms in situ. Several tools have been developed to investigate and quantify the …

Elucidating the chromatin dynamics that orchestrate embryogenesis is a fundamental
question in developmental biology. Here, we exploit position effects on expression as an …

Tissue engineered heart valves are a promising alternative for current heart valve
replacements. However, the mechanical properties of these valves are insufficient for …