Commercial Methods for Antifungal Susceptibility Testing of Saprophytic Molds: Can They Be Used to Detect Resistance?
P Paranos, A Espinel-Ingroff, J Meletiadis - Journal of Fungi, 2024 - mdpi.com
Commercial tests are often employed in clinical microbiology laboratories for antifungal
susceptibility testing of filamentous fungi. Method-dependent epidemiological cutoff values …
susceptibility testing of filamentous fungi. Method-dependent epidemiological cutoff values …
Mitochondrial membrane-associated protein mba1 confers antifungal resistance by affecting the production of reactive oxygen species in aspergillus fumigatus
G Zhu, S Chen, Y Zhang, L Lu - Antimicrobial Agents and …, 2023 - Am Soc Microbiol
Azole resistance in the human fungal pathogen Aspergillus fumigatus is becoming a major
threat to global health. To date, mutations in the azole target-encoding cyp51A gene have …
threat to global health. To date, mutations in the azole target-encoding cyp51A gene have …
The mitochondrial protein Bcs1A regulates antifungal drug tolerance by affecting efflux pump expression in the filamentous pathogenic fungus Aspergillus fumigatus
G Yang, W Shi, W He, J Wu, S Huang, L Mo… - Microbiology …, 2024 - journals.asm.org
Aspergillus fumigatus is the predominant pathogen responsible for aspergillosis infections,
with emerging drug-resistant strains complicating treatment strategies. The role of …
with emerging drug-resistant strains complicating treatment strategies. The role of …
Reversing olorofim activity reveals multifactorial drug tolerance in Aspergillus fumigatus
C Valero, M Mcmanus, AR Anna Durai, J Tindale… - bioRxiv, 2023 - biorxiv.org
Drug tolerance leads to increased cell survival upon antimicrobial treatment and its
contribution to the emergence of antimicrobial resistance is well described in bacteria …
contribution to the emergence of antimicrobial resistance is well described in bacteria …
[HTML][HTML] 唑类药物的耐药机制及结构修饰研究进展
韩云英， 阮奔放 - Advances in Microbiology, 2022 - hanspub.org
侵袭性真菌疾病对公共卫生构成了威胁. 唑类药物可以通过抑制麦角固醇的合成来治疗真菌疾病
, 但唑类药物的广泛使用导致真菌产生了耐药性, 使得临床治疗失败. 所以 …
, 但唑类药物的广泛使用导致真菌产生了耐药性, 使得临床治疗失败. 所以 …
Azolová rezistence u Aspergillus fumigatus: genetický podklad a mechanismy šíření v České republice
K Holíková - 2023 - dspace.cuni.cz
Aspergillus fumigatus je široce rozšířená saprofytická houba, která se často uplatňuje jako
oportunní patogen. Způsobuje onemocnění aspergilózu, která se může projevovat i jako …
oportunní patogen. Způsobuje onemocnění aspergilózu, která se může projevovat i jako …