Outer Membrane Proteins and Efflux Pumps Mediated Multi-Drug Resistance in Salmonella: Rising Threat to Antimicrobial Therapy

SD Akshay, VK Deekshit, J Mohan Raj… - ACS Infectious …, 2023 - ACS Publications
Despite colossal achievements in antibiotic therapy in recent decades, drug-resistant
pathogens have remained a leading cause of death and economic loss globally. One such …

A South African Perspective on the Microbiological and Chemical Quality of Meat: Plausible Public Health Implications

CE Manyi-Loh, R Lues - Microorganisms, 2023 - mdpi.com
Meat comprises proteins, fats, vitamins, and trace elements, essential nutrients for the
growth and development of the body. The increased demand for meat necessitates the use …

Effects of nitrite exposure on the oxidative stress, immune response and intestine microbiota of Procambarus clarkii

DD Bian, YX Shi, XR Zhu, XL Sun, X Xu, L Ding… - Aquaculture, 2024 - Elsevier
Nitrite (NIT) is a toxic nitrogenous compound that adversely affects living organisms. This
study utilized pathological, metagenomic, and transcriptomic analyses to examine the toxic …

Analysis of mcr family of colistin resistance genes in Gram-negative isolates from a tertiary care hospital in India

D Irusan, SD Akshay, VP Shetty… - Journal of Applied …, 2024 - academic.oup.com
Aim Colistin serves as the drug of last resort for combating numerous multidrug-resistant
(MDR) Gram-negative infections. Its efficacy is hampered by the prevalent issue of colistin …

Comparative Genomic Analysis Reveals the Emergence of ST-231 and ST-395 Klebsiella pneumoniae Strains Associated with the High Transmissibility of blaKPC …

M Al-Muzahmi, M Rizvi, M Al-Quraini, Z Al-Muharrmi… - Microorganisms, 2023 - mdpi.com
Conjugative transposons in Gram-negative bacteria have a significant role in the
dissemination of antibiotic-resistance-conferring genes between bacteria. This study aims to …

[HTML][HTML] Integrons in the Age of Antibiotic Resistance: Evolution, Mechanisms, and Environmental Implications: A Review

N Ali, I Ali, AU Din, K Akhtar, B He, R Wen - Microorganisms, 2024 - mdpi.com
Integrons, which are genetic components commonly found in bacteria, possess the
remarkable capacity to capture gene cassettes, incorporate them into their structure, and …

Molecular epidemiology, antibiotic resistance profile and frequency of integron 1 and 2 in adherent-invasive Escherichia coli isolates of colorectal cancer patients

A Heidari, MH Emami, F Maghool… - Frontiers in …, 2024 - frontiersin.org
This study explores the prevalence of adherent-invasive Escherichia coli (AIEC) in colorectal
cancer (CRC) patients and investigates the potential of effective intracellular antibiotics as a …

Understanding Bacterial Resistance to Heavy Metals and Nanoparticles: Mechanisms, Implications, and Challenges

C Prabhu, AU Satyaprasad… - Journal of Basic …, 2024 - Wiley Online Library
Antimicrobial resistance is a global health problem as it contributes to high mortality rates in
several infectious diseases. To address this issue, engineered nanoparticles/nano …

Antibiotic resistance pattern of Methicillin-resistant Staphylococcus aureus isolated from hospitalized patients

F Shamakhte, E Tajbakhsh… - Cellular, Molecular and …, 2024 - cmbr-journal.com
Methicillin-resistant S. aureus (MRSA) strains circulating among populations and crossing
borders constitute a major problem for health control and require a fast and simple genotypic …

CRISPR-Cas System: A New Dawn to Combat Antibiotic Resistance

MS Rafiq, MAB Shabbir, A Raza, S Irshad, A Asghar… - BioDrugs, 2024 - Springer
Antimicrobial resistance (AMR) can potentially harm global public health. Horizontal gene
transfer (HGT), which speeds up the emergence of AMR and increases the burden of drug …