Leishmaniasis in humans: drug or vaccine therapy?

M Ghorbani, R Farhoudi - Drug design, development and therapy, 2017 - Taylor & Francis
Leishmania is an obligate intracellular pathogen that invades phagocytic host cells.
Approximately 30 different species of Phlebotomine sand flies can transmit this parasite …

New world and old world Leishmania infections: a practical review

I Kevric, MA Cappel, JH Keeling - Dermatologic clinics, 2015 - derm.theclinics.com
Leishmaniasis is a tropical disease caused by an intracellular parasite of the genus
Leishmania. The vector of transmission is the sandfly, which deposits one of the 20 disease …

Cutaneous leishmaniasis

R Reithinger, JC Dujardin, H Louzir… - The Lancet infectious …, 2007 - thelancet.com
Cutaneous leishmaniasis is endemic in the tropics and neotropics. It is often referred to as a
group of diseases because of the varied spectrum of clinical manifestations, which range …

Advances in leishmaniasis

HW Murray, JD Berman, CR Davies, NG Saravia - The Lancet, 2005 - thelancet.com
Governed by parasite and host factors and immunoinflammatory responses, the clinical
spectrum of leishmaniasis encompasses subclinical (inapparent), localised (skin lesions) …

[HTML][HTML] Systematic review of the adverse effects of cutaneous leishmaniasis treatment in the New World

LF Oliveira, AO Schubach, MM Martins, SL Passos… - Acta tropica, 2011 - Elsevier
Pentavalent antimonials are first-line drugs for the treatment of the cutaneous form of
American tegumentary leishmaniasis. Second-line drugs include amphotericin B and …

Cutaneous and mucocutaneous leishmaniasis

CV David, N Craft - Dermatologic therapy, 2009 - Wiley Online Library
Leishmaniasis is a cluster of diseases caused by protozoa in the genus Leishmania. There
are three basic clinical forms: cutaneous, mucocutaneous, and visceral leishmaniasis. The …

Diagnosis of leishmaniasis

EK Elmahallawy, AS Martínez… - The Journal of Infection …, 2014 - jidc.org
Leishmaniasis is a clinically heterogeneous syndrome caused by intracellular protozoan
parasites of the genus Leishmania. The clinical spectrum of leishmaniasis encompasses …

Comparison of PCR assays for diagnosis of cutaneous leishmaniasis

E Bensoussan, A Nasereddin, F Jonas… - Journal of clinical …, 2006 - Am Soc Microbiol
Three PCR assays for diagnosing leishmaniasis were compared and validated against
parasite cultures and microscopic evaluation of stained tissue smears using 92 specimens …

Cutaneous leishmaniasis

MS Bailey, DNJ Lockwood - Clinics in dermatology, 2007 - Elsevier
Cutaneous leishmaniasis is a widespread tropical infection caused by numerous different
species of Leishmania protozoa that are transmitted by sandflies. Its clinical presentations …

Cutaneous leishmaniasis treatment

P Minodier, P Parola - Travel medicine and infectious disease, 2007 - Elsevier
The causative species of cutaneous leishmaniasis determines the clinical features and
courses, and treatments. Intralesional or systemic antimonials are the gold standard for the …