Lipids are essential for physiological processes such as maintaining membrane integrity,
providing a source of energy and acting as signalling molecules to control processes …

Adenosine 5′-triphosphate, or ATP, is the primary molecule for storing and transferring
energy in cells. ATP is mainly produced via oxidative phosphorylation in mitochondria, and …

The postnatal mammalian heart undergoes remarkable developmental changes, which are
stimulated by the transition from the intrauterine to extrauterine environment. With birth …

Infants born to diabetic or obese mothers are at greater risk of heart disease at birth and
throughout life, but prevention is hindered because underlying mechanisms remain poorly …

Offspring born to diabetic or obese mothers have a higher lifetime risk of heart disease.
Previously, we found that rat offspring exposed to late-gestational diabetes mellitus (LGDM) …

The dithiocarbamate fungicide maneb (MB) has attracted interest due to increasing concern
of the negative health effects of pesticides, as well as its association with Parkinson's …

Mitochondria in cardiac myocytes are critical for generating ATP to meet the high metabolic
demands associated with sarcomere shortening. Distinct remodeling of mitochondrial …

Left ventricular remodeling due to pressure overload is associated with poor prognosis.
Sacubitril/valsartan is the first-in-class Angiotensin Receptor Neprilysin Inhibitor and has …

The DJ-1 gene, a causative gene for familial Parkinson's disease (PD), has been reported to
have various functions, including transcriptional regulation, antioxidant response, and …

The involvement of mitochondrial uncoupling proteins 2 and 3 in the pathogenesis of
cardiovascular diseases is widely acknowledged. However, contradictory reports show that …