Current methods of adipogenic differentiation of mesenchymal stem cells

MA Scott, VT Nguyen, B Levi… - Stem cells and …, 2011 - liebertpub.com
There has been a recent increase in our understanding in the isolation, culture, and
differentiation of mesenchymal stem cells (MSCs). Concomitantly, the availability of MSCs …

New concepts in white adipose tissue physiology

ARG Proença, RAL Sertié, AC Oliveira… - Brazilian journal of …, 2014 - SciELO Brasil
Numerous studies address the physiology of adipose tissue (AT). The interest surrounding
the physiology of AT is primarily the result of the epidemic outburst of obesity in various …

Kaempferol protects against doxorubicin-induced cardiotoxicity in vivo and in vitro

J Xiao, GB Sun, B Sun, Y Wu, L He, X Wang, RC Chen… - Toxicology, 2012 - Elsevier
The long-term clinical usefulness of doxorubicin (DOX), an anthracycline with potent
antitumor activity, is limited by DOX-induced cardiotoxicity. Kaempferol, one of the most …

Isorhamnetin attenuates atherosclerosis by inhibiting macrophage apoptosis via PI3K/AKT activation and HO-1 induction

Y Luo, G Sun, X Dong, M Wang, M Qin, Y Yu, X Sun - PLoS One, 2015 - journals.plos.org
Background and Purpose Isorhamnetin (Iso) is a flavonoid compound extracted from the
Chinese herb Hippophae rhamnoides L. Previous studies have revealed its anti-cancer, anti …

Notoginsenoside R1 attenuates cardiac dysfunction in endotoxemic mice: an insight into oestrogen receptor activation and PI3K/Akt signalling

B Sun, J Xiao, XB Sun, Y Wu - British journal of pharmacology, 2013 - Wiley Online Library
Background and Purpose Notoginsenoside R1 (NG‐R1), a novel phytoestrogen isolated
from P anax notoginseng, is believed to have anti‐inflammatory, anti‐oxidative and anti …

Myricitrin attenuates endothelial cell apoptosis to prevent atherosclerosis: An insight into PI3K/Akt activation and STAT3 signaling pathways

M Qin, Y Luo, X Meng, M Wang, H Wang, S Song… - Vascular …, 2015 - Elsevier
Blood vessel endothelial dysfunction induced by oxidized low-density lipoprotein (ox-LDL)
has been implicated in the pathogenesis of atherosclerosis and vasculopathy. The ox-LDL …

Isorhamnetin inhibits H2O2‐induced activation of the intrinsic apoptotic pathway in H9c2 cardiomyocytes through scavenging reactive oxygen species and ERK …

B Sun, GB Sun, J Xiao, RC Chen… - Journal of Cellular …, 2012 - Wiley Online Library
As a traditional Chinese medicine, the sea buckthorn (Hippophae rhamnoides L.) has a long
history in the treatment of ischemic heart disease and circulatory disorders. However, the …

Dietary cyanidin 3-glucoside from purple corn ameliorates doxorubicin-induced cardiotoxicity in mice

K Petroni, M Trinei, M Fornari, V Calvenzani… - Nutrition, metabolism …, 2017 - Elsevier
Background and aims Anthracyclines are effective anticancer drugs that have improved
prognosis of hundred thousand cancer patients worldwide and are currently the most …

Total aralosides of Aralia elata (Miq) Seem (TASAES) ameliorate nonalcoholic steatohepatitis by modulating IRE1α-mediated JNK and NF-κB pathways in ApoE …

Y Luo, X Dong, Y Yu, G Sun, X Sun - Journal of Ethnopharmacology, 2015 - Elsevier
Ethnopharmacological relevance Total saponins of Aralia elata (Miq) Seem (TASAES) from
the Chinese traditional herb Long ya Aralia chinensis L. is popularly used as a folk medicine …

CCAAT/enhancer binding protein δ regulates glial proinflammatory gene expression

T Valente, M Straccia, N Gresa-Arribas… - Neurobiology of …, 2013 - Elsevier
The transcription factor CCAAT/enhancer binding protein δ (C/EBPδ) is expressed in
activated astrocytes and microglia and can regulate the expression of potentially detrimental …