The main limitation to the success of central nervous system (CNS) therapies lies in the
difficulty for drugs to cross the blood–brain barrier (BBB) and reach the brain. Regarding its …

The blood–brain barrier (BBB) has shown to be a significant obstacle to brain medication
delivery. The BBB in a healthy brain is a diffusion barrier that prevents most substances from …

Abstract Andrographis paniculata (Burm. f.) Wall. ex Nees, a renowned herb medicine in
China, is broadly utilized in traditional Chinese medicine (TCM) for the treatment of cold and …

Curcumin is a multitherapeutic agent with great therapeutic potential in central nervous
system (CNS) diseases. In the current study, curcumin was encapsulated in solid lipid …

Abstract Background Herbal Nano Medicines (HNMs) are nano-sized medicine containing
herbal drugs as extracts, enriched fractions or biomarker constituents. HNMs have certain …

Barriers are the hallmark of a healthy physiology, blood-brain barrier (BBB) being a tough
nut to crack for most of the antigens and chemical substances. The presence of tight …

Solid lipid nanoparticles (SLN) are considered at the forefront of nanotechnology's rapidly
developing field, with several potential applications in drug delivery and research. SLN …

Recent advancements in drug delivery technologies paved a way for improving cancer
therapeutics. Nanotechnology emerged as a potential tool in the field of drug delivery …

Ethnopharmacological relevance Synthetic drugs used for cancer treatment have side
effects that may be immunosupressive, can cause liver, kidney and cardiac toxicity, and …

The aim of the present study was the development of human serum albumin nanoparticles
(HSA NPs) as nose-to-brain carrier. To strengthen, the efficacy of nanoparticles as drug …