Mapping specificity, cleavage entropy, allosteric changes and substrates of blood proteases in a high-throughput screen
Proteases are among the largest protein families and critical regulators of biochemical
processes like apoptosis and blood coagulation. Knowledge of proteases has been …
processes like apoptosis and blood coagulation. Knowledge of proteases has been …
Sensitive identification of known and unknown protease activities by unsupervised linear motif deconvolution
The cleavage-site specificities for many proteases are not well understood, restricting the
utility of supervised classification methods. We present an algorithm and web interface to …
utility of supervised classification methods. We present an algorithm and web interface to …
Cognitive framework for HIV-1 protease cleavage site classification using evolutionary algorithm
Acquired immunodeficiency syndrome is the progression from human immunodeficiency
virus (HIV) to symptomatic disease. The disease process starts by replicating the viral …
virus (HIV) to symptomatic disease. The disease process starts by replicating the viral …
Revealing favorable and unfavorable residues in cooperative positions in protease cleavage sites
Proteases play critical roles in a wide variety of fundamental biological functions, and
numerous protease inhibitors have been developed to treat various diseases including …
numerous protease inhibitors have been developed to treat various diseases including …
[PDF][PDF] Insights into protease sequence similarities by comparing substrate sequences and phylogenetic dynamics
E Qi, C Fu, Y Zhai, J Dong - Mathematical Biosciences and …, 2021 - aimspress.com
Based on substrate sequences, we proposed a novel method for comparing sequence
similarities among 68 proteases compiled from the MEROPS online database. The rank …
similarities among 68 proteases compiled from the MEROPS online database. The rank …
Mapping specificity, entropy, allosteric changes and substrates in blood proteases by a high-throughput protease screen
F Uliana, M Vizovišek, L Acquasaliente, R Ciuffa… - bioRxiv, 2020 - biorxiv.org
Proteases are among the largest protein families in eukaryotic phylae with more than 500
genetically encoded proteases in humans. By cleaving a wide range of target proteins …
genetically encoded proteases in humans. By cleaving a wide range of target proteins …
[引用][C] Investigating the specificity of peptidases: Scientific relevance and functional implications for cellular dynamics.
RR da Silva - Journal of Cellular Biochemistry, 2018 - europepmc.org
Investigating the specificity of peptidases: Scientific relevance and functional implications for
cellular dynamics. - Abstract - Europe PMC Sign in | Create an account https://orcid.org Europe …
cellular dynamics. - Abstract - Europe PMC Sign in | Create an account https://orcid.org Europe …