Proteomics can be viewed as an experimental approach to explain the information
contained in genomic sequences in terms of the structure, function, and control of biological …

Proteome analysis implies the ability to separate proteins as a first step prior to
characterization. Thus, the overall performance of the analysis strongly depends on the …

Proteomic research, for its part, is benefiting enormously from the last decade of genomic
research as we now have archived, annotated and audited sequence databases to correlate …

Early detection is critical in cancer control and prevention. Biomarkers help in this process
by providing valuable information about a the status of a cell at any given point in time. As a …

A comprehensive on-line two-dimensional 2D-HPLC system with integrated sample
preparation was developed for the analysis of proteins and peptides with a molecular weight …

Proteomics has emerged as an indispensable methodology for large-scale protein analysis
in functional genomics. The Escherichia coli proteome has been extensively studied and is …

We introduce a computational method for identifying subcellular locations of proteins from
the phylogenetic distribution of the homologs of organellar proteins. This method is based …

Separation and relative quantitation of complex protein mixtures remain two of the most
challenging aspects of proteomics. Here an advanced technique called fluorescence …

Abstract The Gram negative bacterium Helicobacter pylori is a human pathogen which
infects the gastric mucosa and causes an inflammatory process leading to gastritis …

Biomarkers provide a powerful and dynamic approach to understanding the spectrum of
malignancies with applications in observational and analytic epidemiology, randomized …