Meningiomas are the most common intracranial tumors. Yet, only few controlled clinical trials
have been conducted to guide clinical decision making, resulting in variations of …

Brain tumors, although rare, contribute to distinct mortality and morbidity at all ages.
Although there are few therapeutic options for brain tumors, enhanced biological …

Meningiomas are the most common primary intracranial tumors. There are no effective
medical therapies for meningioma patients, and new treatments have been encumbered by …

Hedgehog signaling mediates embryologic development of the central nervous system and
other tissues and is frequently hijacked by neoplasia to facilitate uncontrolled cellular …

Meningiomas are classified based on histological features, but genetic and epigenetic
features are emerging as relevant biomarkers for outcome prediction and may supplement …

Background Meningiomas, the most common primary intracranial tumors, can be separated
into 3 DNA methylation groups with distinct biological drivers, clinical outcomes, and …

Simple Summary Since the initial publication of the Simpson Grade scale, the management
paradigm for intracranial meningiomas has significantly evolved. The generalized …

Surgery is the mainstay of treatment for meningioma, the most common primary intracranial
tumor, but improvements in meningioma risk stratification are needed and indications for …

Meningiomas are the most common primary intracranial tumors in adults and are increasing
in incidence due to the aging population and increased access to neuroimaging. While most …

CDKN2A inactivation or TERT promoter mutation are new criteria for World Health
Organization (WHO) grade 3 meningiomas [9]. These infrequent alterations can occur in …