The pandemics of obesity and type 2 diabetes have become a concern of public health.
Nutrition plays a key role in these concerns. Insulin as an anabolic hormonal was …

Glaucoma is a complex multifactorial eye disease manifesting in retinal ganglion cell (RGC)
death and optic nerve degeneration, ultimately causing irreversible vision loss. Research in …

The study aimed to explore the association between sleep duration, insomnia symptoms
and the components of metabolic syndrome (MetS) among middle-aged and older adults. A …

Previously, the RXR agonist UAB126 demonstrated therapeutic potential to treat obese mice
by controlling blood glucose levels (BGL) and altering the expression of genes associated …

BACKGROUND Obesity has become a serious public health issue, significantly elevating
the risk of various complications. It is a well-established contributor to Heart failure with …

9-cis-retinoic acid (9cRA) binds retinoic acid receptors (RAR) and retinoid X receptors (RXR)
with nanomolar affinities, in contrast to all-trans-retinoic acid (atRA), which binds only RAR …

The onset of metabolic dysfunction-associated steatohepatitis (MASH) or non-alcoholic
steatohepatitis (NASH) represents a tipping point leading to liver injury and subsequent …

Impaired insulin secretion is one of the main causes of type 2 diabetes. Cholesterol
accumulation-induced lipotoxicity contributes to impaired insulin secretion in pancreatic beta …

Most allogeneic hematopoietic stem cell transplant (allo-HSCT) recipients receive peripheral
blood stem cell grafts resulting in a 30%–70% incidence of chronic graft-versus-host disease …

Nitric oxide (NO) is a gaseous signaling molecule, which plays crucial roles in various
biological processes, including inflammatory responses, metabolism, cardiovascular …