The cause–effect relation of tuberculosis on incidence of diabetes mellitus

MK Bisht, P Dahiya, S Ghosh… - Frontiers in cellular and …, 2023 - frontiersin.org
Tuberculosis (TB) is one of the oldest human diseases and is one of the major causes of
mortality and morbidity across the Globe. Mycobacterium tuberculosis (Mtb), the causal …

Acid-Fast Positive and Acid-Fast Negative Mycobacterium tuberculosis: The Koch Paradox

C Vilchèze, L Kremer - Microbiology spectrum, 2017 - Am Soc Microbiol
ABSTRACT Acid-fast (AF) staining, also known as Ziehl-Neelsen stain microscopic
detection, developed over a century ago, is even today the most widely used diagnostic …

Endocannabinoids inhibit the induction of virulence in enteric pathogens

M Ellermann, AR Pacheco, AG Jimenez, RM Russell… - Cell, 2020 - cell.com
Endocannabinoids are host-derived lipid hormones that fundamentally impact
gastrointestinal (GI) biology. The use of cannabis and other exocannabinoids as anecdotal …

The microbiome and gut endocannabinoid system in the regulation of stress responses and metabolism

RK Srivastava, B Lutz, I Ruiz de Azua - Frontiers in cellular …, 2022 - frontiersin.org
The endocannabinoid system, with its receptors and ligands, is present in the gut epithelium
and enteroendocrine cells, and is able to modulate brain functions, both indirectly through …

Reversible lipid accumulation and associated division arrest of Mycobacterium avium in lipoprotein-induced foamy macrophages may resemble key events during …

I Caire-Brändli, A Papadopoulos, W Malaga… - Infection and …, 2014 - Am Soc Microbiol
During the dormant phase of tuberculosis, Mycobacterium tuberculosis persists in lung
granulomas by residing in foamy macrophages (FM) that contain abundant lipid bodies (LB) …

Small-Molecule Probes Reveal Esterases with Persistent Activity in Dormant and Reactivating Mycobacterium tuberculosis

KR Tallman, SR Levine, KE Beatty - ACS infectious diseases, 2016 - ACS Publications
Mycobacterium tuberculosis (Mtb) is the deadliest bacterial pathogen in the world. An
estimated one-third of humans harbor Mtb in a dormant state. These asymptomatic, latent …

Nitrogen deprivation induces triacylglycerol accumulation, drug tolerance and hypervirulence in mycobacteria

P Santucci, MD Johansen, V Point, I Poncin, A Viljoen… - Scientific reports, 2019 - nature.com
Mycobacteria share with other actinomycetes the ability to produce large quantities of
triacylglycerol (TAG), which accumulate as intracytoplasmic lipid inclusions (ILI) also known …

Experimental models of foamy macrophages and approaches for dissecting the mechanisms of lipid accumulation and consumption during dormancy and reactivation …

P Santucci, F Bouzid, N Smichi, I Poncin… - Frontiers in cellular …, 2016 - frontiersin.org
Despite a slight decline since 2014, tuberculosis (TB) remains the major deadly infectious
disease worldwide with about 1.5 million deaths each year and with about one-third of the …

Mycobacterium tuberculosis Lipolytic Enzymes as Potential Biomarkers for the Diagnosis of Active Tuberculosis

B Brust, M Lecoufle, E Tuaillon, L Dedieu, S Canaan… - PloS one, 2011 - journals.plos.org
Background New diagnosis tests are urgently needed to address the global tuberculosis
(TB) burden and to improve control programs especially in resource-limited settings. An …

Mycobacterial lipolytic enzymes: a gold mine for tuberculosis research

L Dedieu, C Serveau-Avesque, L Kremer, S Canaan - Biochimie, 2013 - Elsevier
Tuberculosis (TB) is one of the deadliest infectious diseases worldwide with a strong impact
in developing countries. Mycobacterium tuberculosis, the etiological agent of TB, has a high …