Tumor cells transmit drug resistance via cisplatin-induced extracellular vesicles

J Wang, Q Liu, Y Zhao, J Fu, J Su - International Journal of Molecular …, 2023 - mdpi.com
Cisplatin is a first-line clinical agent used for treating solid tumors. Cisplatin damages the
DNA of tumor cells and induces the production of high levels of reactive oxygen species to …

Expedition into exosome biology: a perspective of progress from discovery to therapeutic development

AT Jan, S Rahman, R Badierah, EJ Lee, EH Mattar… - Cancers, 2021 - mdpi.com
Simple Summary Exosomes symbolize membrane-enclosed entities of endocytic origin.
They play an important role in the intracellular communication by shuttling proteins, nucleic …

Multi-omics data integration in extracellular vesicle biology—utopia or future reality?

L Chitoiu, A Dobranici, M Gherghiceanu… - International journal of …, 2020 - mdpi.com
Extracellular vesicles (EVs) are membranous structures derived from the endosomal system
or generated by plasma membrane shedding. Due to their composition of DNA, RNA …

Proteomic signature of extracellular vesicles for lung cancer recognition

SE Novikova, NA Soloveva, TE Farafonova… - Molecules, 2021 - mdpi.com
The proteins of extracellular vesicles (EVs) that originate from tumors reflect the producer
cells' proteomes and can be detected in biological fluids. Thus, EVs provide proteomic …

Complement in tumourigenesis and the response to cancer therapy

RM O'Brien, A Cannon, JV Reynolds, J Lysaght… - Cancers, 2021 - mdpi.com
Simple Summary Increasing evidence supports a role for complement in the development of
cancer and the response to cancer treatments. Dysregulated complement expression within …

Air pollution and lung cancer: contributions of extracellular vesicles as pathogenic mechanisms and clinical utility

J González-Ruíz, A A. Baccarelli… - Current Environmental …, 2023 - Springer
Abstract Purpose of Review This review addresses the pressing issue of air pollution's threat
to human health, focusing on its connection to non-small cell lung cancer (NSCLC) …

[HTML][HTML] Label-free optical redox ratio from urinary extracellular vesicles as a screening biomarker for bladder cancer

J Park, RL Kamerer, M Marjanovic… - American Journal of …, 2022 - ncbi.nlm.nih.gov
Extracellular vesicles (EVs) have been studied for their potential applications in cancer
screening, diagnosis, and treatment monitoring. Most studies have focused on the bulk …

Comparative proteomic profiling of cisplatin-resistant nasopharyngeal carcinoma cell lines: novel biomarkers for improving chemotherapy of NPC

P Prathaphan, O Reamtong, U Ngaokrajang… - Anticancer …, 2022 - ar.iiarjournals.org
Background/Aim: Nasopharyngeal carcinoma (NPC) originates in the hidden nasopharynx,
causing NPC patients to be diagnosed at a late stage and develop drug resistance …

[PDF][PDF] Complement in Tumourigenesis and the Response to Cancer Therapy. Cancers 2021, 13, 1209

RM O'Brien, A Cannon, JV Reynolds, J Lysaght… - 2021 - pdfs.semanticscholar.org
In recent years, our knowledge of the complement system beyond innate immunity has
progressed significantly. A modern understanding is that the complement system has a …