Psoriasis is an immune-mediated genetic skin disease. The underlying pathomechanisms
involve complex interaction between the innate and adaptive immune system. T cells …

Psoriasis has long been known as a disease with many complications, but was attributed to
diet and obesity. However, in recent years, psoriasis itself has been recognized as a series …

Background The composition of bacteria in and on the human body varies widely across
human individuals, and has been associated with multiple health conditions. While microbial …

In the last decades, autoimmune diseases have experienced a dramatic increase in Western
countries. The involvement of environmental factors is strongly suspected to explain this rise …

After its discovery as a key controller of metabolic function, leptin has been later extensively
implicated in additional functions including important modulatory activities on the innate and …

Psoriasis is a common inflammatory skin disease characterized by the appearance of red
scaly plaques that can affect any part of the body. High prevalence, chronicity, disfiguration …

Psoriasis is a common chronic inflammatory skin disease with a complex pathogenesis
consisting of a genetic component, immune dysfunction, and environmental factors. It is …

Psoriasis is a chronic systemic inflammatory disorder associated with several comorbidities
in addition to the characteristic skin lesions. Metabolic syndrome (MetS) is the most frequent …

Psoriasis is now classified as an immune-mediated inflammatory disease (IMID) of the skin.
It is being recognized that patients with various IMIDs, including psoriasis, are at higher risk …

There is increasing awareness that psoriasis is more than 'skin deep'. Several recent
reviews focussed on biomarkers indicating the systemic dimension of psoriasis and the …