Advances in saponin-based adjuvants

HX Sun, Y Xie, YP Ye - Vaccine, 2009 - Elsevier
Saponins are natural glycosides of steroid or triterpene which exhibited many different
biological and pharmacological activities. Notably, saponins can also activate the …

Vaccines for leishmaniasis in the fore coming 25 years

CB Palatnik-de-Sousa - Vaccine, 2008 - Elsevier
Human vaccination against leishmaniasis using live Leishmania was used in Middle East
and Russia (1941–1980). First-generation vaccines, composed by killed parasites induce …

Vaccine candidates for leishmaniasis: a review

R Nagill, S Kaur - International immunopharmacology, 2011 - Elsevier
Leishmaniasis is a diverse group of clinical syndromes caused by protozoan parasites of the
genus Leishmania. The clinical manifestation of the disease varies from self-limiting …

Protective immunity against challenge with Leishmania (Leishmania) chagasi in beagle dogs vaccinated with recombinant A2 protein

AP Fernandes, MMS Costa, EAF Coelho… - Vaccine, 2008 - Elsevier
In this study, we investigated in dogs the immunogenicity and protective immunity against
Leishmania (Leishmania) chagasi infection induced by vaccination with a formulation …

[HTML][HTML] Vaccination in leishmaniasis: a review article

L Abdellahi, F Iraji, A Mahmoudabadi… - Iranian Biomedical …, 2022 - ncbi.nlm.nih.gov
Leishmaniasis is caused by protozoan Leishmania parasites that are transmitted through
female sandfly bites. The disease is predominantly endemic to the tropics and semi-tropics …

Haemolytic activities and adjuvant effect of Astragalus membranaceus saponins (AMS) on the immune responses to ovalbumin in mice

ZG Yang, HX Sun, WH Fang - Vaccine, 2005 - Elsevier
In this study, the haemolytic activities of Astragalus membranaceus saponins (AMS) and its
adjuvant potentials on the cellular and humoral immune responses of ICR mice against OVA …

Immunity to Leishmania and the rational search for vaccines against canine leishmaniasis

AB Reis, RC Giunchetti, E Carrillo, OA Martins-Filho… - Trends in …, 2010 - cell.com
The control of infection by Leishmania infantum (syn. Leishmania chagasi) in dogs is
essential to stop the current spread of zoonotic visceral leishmaniasis. The past few years …

Plant-derived immuno-adjuvants in vaccines formulation: a promising avenue for improving vaccines efficacy against SARS-CoV-2 virus

A Kumar, A Sharma, NV Tirpude, Y Padwad… - Pharmacological …, 2022 - Springer
The SARS-CoV-2 outbreak has posed a plethora of problems for the global healthcare
system and socioeconomic burden. Despite valiant efforts to contain the COVID-19 …

Vaccines for canine leishmaniasis

CB Palatnik-de-Sousa - Frontiers in immunology, 2012 - frontiersin.org
Leishmaniasis is the third most important vector-borne disease worldwide. Visceral
leishmaniasis (VL) is a severe and frequently lethal protozoan disease of increasing …

[HTML][HTML] Selection of adjuvants for enhanced vaccine potency

W Wang, M Singh - World Journal of Vaccines, 2011 - scirp.org
The advent of mass vaccination has saved millions of human lives and revolutionized the
quality of life. Vaccination is currently one of the most cost effective ways of managing …