New angiogenic regulators produced by TAMs: perspective for targeting tumor angiogenesis
I Larionova, E Kazakova, T Gerashchenko… - Cancers, 2021 - mdpi.com
Simple Summary Since the targeting of a single pro-angiogenic factor fails to improve
oncological disease outcome, significant efforts have been made to identify new pro …
oncological disease outcome, significant efforts have been made to identify new pro …
Challenges and opportunities for celecoxib repurposing
U Bąk, A Krupa - Pharmaceutical Research, 2023 - Springer
Drug repositioning, also known as drug repurposing, reprofiling, or rediscovery, is
considered to be one of the most promising strategies to accelerate the development of new …
considered to be one of the most promising strategies to accelerate the development of new …
Phenolic phytochemicals for prevention and treatment of colorectal cancer: A critical evaluation of in vivo studies
S De, S Paul, A Manna, C Majumder, K Pal, N Casarcia… - Cancers, 2023 - mdpi.com
Simple Summary Colorectal cancer (CRC) is a significant cause of death worldwide. The
inefficacy of the current treatment regimens is reflected in the frequent recurrence and …
inefficacy of the current treatment regimens is reflected in the frequent recurrence and …
Investigating the therapeutic promise of drug-repurposed-loaded nanocarriers: A pioneering strategy in advancing colorectal cancer treatment
Globally, colorectal cancer is a major health problem that ranks in third place in terms of
occurrences and second in terms of mortality worldwide. New cases increase annually, with …
occurrences and second in terms of mortality worldwide. New cases increase annually, with …
Aspirin sensitivity of PIK3CA-mutated Colorectal Cancer: potential mechanisms revisited
DCN Hall, RA Benndorf - Cellular and Molecular Life Sciences, 2022 - Springer
PIK3CA mutations are amongst the most prevalent somatic mutations in cancer and are
associated with resistance to first-line treatment along with low survival rates in a variety of …
associated with resistance to first-line treatment along with low survival rates in a variety of …
Therapeutic effects of natural polyphenols on colorectal adenomas: Focus on preclinical studies
F Ma, Y Lin, Z Ni, T Chen, X Wang - Oncology Reports, 2023 - spandidos-publications.com
Colorectal adenoma (CRA) is a premalignant lesion of colorectal cancer. The current
treatment is surgical resection, but CRA is prone to recurrence, and there is no safe and …
treatment is surgical resection, but CRA is prone to recurrence, and there is no safe and …
New pyridazine derivatives as selective COX-2 inhibitors and potential anti-inflammatory agents; design, synthesis and biological evaluation
New pyridazinone and pyridazinthione derivatives were designed, synthesized and
identified through performing 1 H NMR, 13 C NMR, IR and MS spectroscopic techniques. All …
identified through performing 1 H NMR, 13 C NMR, IR and MS spectroscopic techniques. All …
[HTML][HTML] Role of cyclooxygenase-2 in colorectal cancer
Cyclooxygenase-2 (COX-2) is an inducible enzyme which triggers the biosynthesis of
prostaglandins. COX-2 is activated in response to inflammatory stimuli and is one of the …
prostaglandins. COX-2 is activated in response to inflammatory stimuli and is one of the …
Network pharmacology and molecular docking on the molecular mechanism of Luo-hua-zi-zhu (LHZZ) granule in the prevention and treatment of bowel precancerous …
C Guo, X Kang, F Cao, J Yang, Y Xu, X Liu… - Frontiers in …, 2021 - frontiersin.org
The Luo-hua-zi-zhu (LHZZ) granule has been widely used for the treatment of colorectal
adenoma (CRA), which is a precursor of colorectal cancer (CRC). However, the active …
adenoma (CRA), which is a precursor of colorectal cancer (CRC). However, the active …
结直肠腺瘤性息肉术后复发的中西医治疗进展
钟彩玲， 王阿玲， 赵喜颖， 李叶， 张北平 - 中国中西医结合消化杂志, 2019 - whuhzzs.com
者进行危险分层, 低风险腺瘤(LRA): 管状腺瘤1~ 2 个, 腺瘤< 10mm; 高风险腺瘤(HRA):
腺瘤含有绒毛成分或高度异型增生, 或腺瘤≥ 10mm 以及或3 个以上的腺瘤[9] …
腺瘤含有绒毛成分或高度异型增生, 或腺瘤≥ 10mm 以及或3 个以上的腺瘤[9] …