Introduction Psoriasis is a chronic inflammatory skin disease that may have an important
negative impact on a patient's quality of life. Biological agents deeply changed the …

Psoriasis is a skin disease that is not lethal and does not spread through bodily contact.
However, this seemingly harmless condition can lead to a loss of confidence and social …

Psoriasis is a chronic inflammatory skin disorder that affects approximately 2–3% of the
population worldwide and has severe effects on patients' physical and psychological well …

Being one of the most common dermatological inflammatory disorders, psoriasis is a
frequent subject of research. It is considered to be a T cell-dependent immune disease …

Bullous pemphigoid (BP) is a severe autoimmune blistering skin disorder that primarily
causes disease in the older population and is the most prevalent subepidermal variant of the …

Tyrosine kinase 2 (TYK2) is a nonreceptor tyrosine kinase that belongs to the JAK family
also comprising JAK1, JAK2, and JAK3. TYK2 is an attractive target for various autoimmune …

Background Psoriasis is one of the most common chronic cutaneous skin disorders, having
genetic and immunological components. It is currently unknown what exactly triggers it, or …

Understanding the factors creating genetic susceptibility in psoriasis may provide a basis for
improving targeted treatment strategies. In this review, we discuss the genes linked to the …

Psoriasis is a chronic and debilitating inflammatory immune-mediated skin disorder. Several
cytokines including interleukin (IL)-23 were demonstrated to play a central role in the …

Tumor necrosis factor (TNF) inhibitors, the first biological immunomodulators, bind TNF
glycoprotein, the receptor of which is present in numerous immune and tissuespecific cells …