Abstract Prostaglandin E 2 (PGE 2) is a bioactive lipid that elicits a wide range of biological
effects associated with inflammation and cancer. PGE 2 exerts diverse effects on cell …

Patients with ulcerative colitis (UC) are at a two-to three-fold increased risk of developing
colorectal cancer (CRC) than the general population based on population-based data. UC …

Associations between microRNAs (miRNAs) and human diseases have been identified by
increasing studies and discovering new ones is an ongoing process in medical laboratories …

Chemo-resistance and metastasis of triple negative breast cancer (TNBC) contributed the
most of treatment failure in the clinic. MicroRNAs (miRNAs) have been proved to be involved …

Osteosarcoma is the most common high-grade human primary malignant bone sarcoma
with lower survival in the past decades. Oridonin, a bioactive diterpenoid isolated from …

Colorectal cancer (CRC) is the second leading cause of cancer‐related mortality in Western
countries. Although the aberrant expression of several microRNAs (oncomiRs) is associated …

MicroRNAs (miRNAs) are small noncoding RNAs that could regulate gene expressions
transcriptionally or post-transcriptionally through binding to 3'untranslated region (3'UTR) of …

We previously showed that high expression levels of SOX9 correlate with hepatocellular
carcinoma (HCC) progression. However, the exact role that SOX9 plays in HCC remains …

Cyclooxygenase-2 is frequently upregulated in epithelial tumors and contributes to poor
outcomes in multiple malignancies. The COX-2 product prostaglandin E2 (PGE2) promotes …

Small noncoding RNAs perform multiple regulatory functions in cells, and their exogenous
mimics are widely used in research and experimental therapies to interfere with target gene …